China’s first "cell knife" surgery for 20 years: the "brave" dance on the tip of the knife

  He pioneered functional neurosurgery in China and was the "first person in cell knife" in China … … In the field of functional neurosurgery in China, Li Yongjie is a "myth". Under the dazzling aura, in essence, he will always be a scientist doctor who constantly explores new fields and a doctor who stands in the way of death and disease.

  Li Yongjie is a 79-grade college student — — After the reform and opening up, the first batch of college students changed their fate through the college entrance examination. In the early 1990s, with the tide of studying abroad, he learned "one-handed" skills in traveling to the west. Although he got the green card, he resolutely gave up the choice of returning to China. In just 20 years, he created and led a discipline to rank among the international "first phalanx" … …

  At the time of 40 years of reform and opening up, the 1.5 million-word book Functional Neurosurgery edited by Li Yongjie was published. A book, a person; A discipline, an era … …

  Open Functional Neurosurgery, walk into xuanwu hospital Institute of Functional Neurosurgery and Beijing Institute of Functional Neurosurgery of Capital Medical University, approach Li Yongjie’s team, and learn about the development of functional neurosurgery, as if seeing the dance of "brave" on the tip of a knife, and the wonderful dance skills are the never-ending steps … …

▲ Family photo of 2018 Beijing Institute of Functional Neurosurgery. Photo courtesy of respondents

▲ Family photo of 2018 Beijing Institute of Functional Neurosurgery. Photo courtesy of respondents

  Xinhua Daily Telegraph Press Conference Morality

  At the fork of Zheng Xinyi’s fate, Li Yongjie, his attending doctor and director of Beijing Institute of Functional Neurosurgery, stood there with a smile — — It was he and his team who realized the dream that "China Forrest Gump" had broken one place through surgery.

  July 12th is the 20th anniversary of the first "cell knife" operation in China. Xinhua Daily Telegraph reporter entered the organization that has become the largest number of brain pacemakers implanted in the world for 10 consecutive years — — Xuanwu hospital Institute of Functional Neurosurgery and Beijing Institute of Functional Neurosurgery of Capital Medical University.

  He was admitted to Peking University in 1979, studied abroad in 1994, and returned to China 20 years ago to establish the Beijing Institute of Functional Neurosurgery. A few years ago, he began to explore the society to run doctors and set up outpatient departments to help more people see and be optimistic about the disease … … In the recent 40 years, Li Yongjie’s fate has been closely linked with the changes of a discipline and an era.

▲ Professor Li Yongjie.

▲ Professor Li Yongjie.

  Open your eyes and see the world:

  From "the first person in cell knife" to "a seed"

  The human brain is one of the most amazing and complicated substances in the world. To move a "knife" on the brain requires not only courage, but also "real kung fu".

  The operation that Li Yongjie cured Zheng Xinyi was called "Deep Brain Stimulation Operation". Simply put, it is to put electrodes deep in the human brain. The scientific principle is that the dyskinesia of human body is caused by pathological changes in some brain cells, and their symptoms can be controlled and regulated by electrical stimulation of the pathological cells.

▲ Professor Li Yongjie performs stereotactic surgery for patients.

▲ Professor Li Yongjie performs stereotactic surgery for patients.

  Such an operation sounds simple, but in fact, human beings didn’t realize the relationship between human brain and consciousness and behavior until the end of the 19th century. The accurate treatment of brain tissue by surgery can be traced back to the emergence of stereotactic technology in 1947 — — At that time, the disease targeted by this technology was Parkinson’s disease, which was called "immortal cancer".

  At first, the patient’s hands and feet showed rhythmic tremor, slow movement, difficulty in tying shoelaces and buttons, and difficulty in putting on and taking off shoes and socks. After 5 to 15 years of illness, he gradually lost his mobility … … Parkinson’s disease is a slowly progressive disease, which mainly occurs in middle-aged and elderly people. Muhammad Ali and mathematician Chen Jingrun all suffered from this disease.

  In 1994, Li Yongjie, who had just gone abroad for postdoctoral studies, first came into contact with the cutting-edge microelectrode-guided stereotactic neurosurgery. This is a technique to stop the patient’s body tremor by destroying the "tremor cells" in the brain, which is vividly called "cell knife".

  As a neuromodulation surgery, it uses stereotactic method to locate accurately, implants stimulation electrodes in the human brain, and controls the stimulation parameters of the electrodes in the brain through the remote control device in vitro, so as to control and improve the patient’s disease symptoms. It is the most successful case for human beings to realize the dream of "brain-computer dialogue".

  "This kind of deep brain stimulator, also known as brain pacemaker, is the most advanced technical means for the treatment of functional encephalopathy in the international medical community since the beginning of the 21 ST century, among which the treatment of Parkinson’s disease patients is the most mature and common." Today, Li Yongjie still remembers the shock of that moment.

  After the patient who was treated in the operating room was accurately located in the skull, a very thin electrode went deep into her brain to find the abnormal cells, and then it was "destroyed" by radio frequency heating. Within a few seconds, the violent tremor of the patient’s right hand disappeared, and her tears welled up in her eyes: "Oh, my God, it’s stopped for 10 years … …”

▲ The Institute was established in 1998-Dr. RP-Iacono, a famous functional neurosurgeon from the United States, came to congratulate him personally.

▲ The Institute was established in 1998-Dr. RP-Iacono, a famous functional neurosurgeon from the United States, came to congratulate him personally.

  "The whole world seems to be silent, and I can only hear the voice in my heart: I must master this technology!" Li Yongjie, 57, will never forget the moment when he decided his future academic direction and even his life destiny.

  At that time, this advanced surgical technique was still a blank in China, and doctors also called Parkinson’s disease "tremor paralysis". Li Yongjie, who has been a doctor of medicine in China for several years, knows very well that there are tens of millions of patients with nervous system functional diseases like Parkinson’s disease in China, and high-level brain surgery intervention is urgently needed.

  After graduating as a postdoctoral fellow, Li Yongjie did not hesitate to join the world-renowned stereotactic neurosurgery — — The medical center of Linda University in Rome has mastered all the techniques of "cell knife" in only two years.

  "There are so many patients in China, I want to go back to China and bring back the technology I have learned!" Li Yongjie’s inner voice rang again. Comfortable life, clean environment, American green card … … Nothing can stop him from returning to China.

  "I left without hesitation." Li Yongjie said firmly.

▲ On July 12th, 1998, Li Yongjie completed the first stereotactic cell knife operation in Beijing Institute of Functional Neurosurgery.

▲ On July 12th, 1998, Li Yongjie completed the first stereotactic cell knife operation in Beijing Institute of Functional Neurosurgery.

  On July 12th, 1998, the first "cell knife" operation in China began in xuanwu hospital. Li Yongjie, who returned from school, is a surgeon, anesthesiologist, radiologist and nurse … … Because no one knows how this "sophisticated" operation is done, he needs to personally control every link.

  Heading, taking the patient to the nuclear magnetic room for brain scanning, positioning the surgical target, calculating the target position, craniotomy, drilling, inserting a very fine puncture needle to reach the target position, and inserting a microelectrode &hellip along the needle track; … Unconsciously, eight hours passed, and Li Yongjie, who was immersed in it, didn’t feel it at all. The doctors and nurses on the sidelines saw that the error of electrode positioning was less than 1 mm, and the patient’s trembling hand gradually stopped during the operation.

  "The human brain is a black box. Stereotactic technology is a bit like GPS and must be accurate to the millimeter." Li Yongjie said.

  Functional Neurosurgery Newsletter is a peer-to-peer exchange publication run by the Institute. The cover of the 10th issue published in April 2012 is a picture of Swiss national hero william tell aiming at an apple on his son’s head not far away under the oppression of colonists.

  "Through the distant time and space, we are capturing William’s breath in the picture, pulse diagnosis’s pulse, and appreciate each other’s heart is sympathetic." Li Yongjie wrote in the article "Courage and Responsibility Create Glory" on the front page of the magazine, "Because our profession is a doctor who saves lives, and the disease is ‘ Magic ’ The doctor is a bow and arrow maker. Facing the eyes of patients seeking help or even despair, facing the challenges of difficult and complicated diseases, and facing the medical risks and sociological risks brought by treatment, we are tested and challenged every day. This not only requires our confidence in our own knowledge and skills, but also challenges our courage and responsibility. "

  Neurosurgery, especially stereotactic surgery, is like shooting an apple with a bow.

  "This requires a high degree of accuracy, and no mistakes are allowed, so as to ensure that patients are safe, and ‘ Shoot ’ The disease is invisible. " Li Yongjie said.

  "It feels amazing." Lu Xiaoli, a doctor who witnessed the whole operation, remembers that after the success of the operation, more and more patients came here. By the end of 1998, Li Yongjie’s team had been able to perform dozens of "cell knife" operations every month, and a set of scientific operation standard procedures were established, and the operation time was shortened to an average of two hours.

  "I am just a seed, bringing this technology back to China and blossoming everywhere." Li Yongjie, who is known as the "first person of cell knife", said modestly that if he has made any contribution, it is to make the stereotactic technology develop more finely and safely in China.

▲ In 1999, the National Parkinson Foundation awarded Beijing Institute of Functional Neurosurgery the title of "Clinical Center of Excellence".

▲ In 1999, the National Parkinson Foundation awarded Beijing Institute of Functional Neurosurgery the title of "Clinical Center of Excellence".

  Parkinson’s disease is the most common type of dyskinesia. Epidemiological statistics show that there are 2 million patients in China, accounting for 40% of the total number of patients in the world. Due to the aging of the population, the incidence of Parkinson’s disease is still increasing, and it has become one of the common diseases in the nervous system of middle-aged and elderly people.

  In 1817, the British doctor Parkinson confirmed Parkinson’s disease in his book "On Tremor Paralysis", and then the international medical community named the disease after him.

  "This year is 201 years since Parkinson’s disease was confirmed." Li Yongjie said, "Before I went abroad, the name Parkinson’s disease had been used abroad for more than 100 years, and this disease was still called ‘ Tremor paralysis ’ . Now the country is also called Parkinson’s disease, which is the result of everyone opening their eyes to see the world. "

  The pioneering and exploration of Beijing Institute of Functional Neurosurgery has made countless patients see hope.

  As of July 12, 2018, in the past 20 years, Beijing Institute of Functional Neurosurgery has performed stereotactic surgery for 6,690 patients with dyskinesia, involving 13 types of functional neurosurgical diseases: Parkinson’s disease accounts for more than 3/4, followed by primary tremor (10.87%) and dystonia (7.17%), and other dyskinesia only accounts for 5.74%— — Include cerebral palsy, TIC disorder, Parkinson’s superposition syndrome, voluntary movement’s disease, chorea, etc.

  "At the beginning of returning to China for three or five years, we were fighting alone. In the last five or six years, hospitals and universities everywhere can’t wait to develop functional neurosurgery. " Li Yongjie said.

▲2009-9-18- Professor Ali-Rezai, an American expert on dyskinesia, visited and Professor Li Yongjie signed a book.

▲2009-9-18- Professor Ali-Rezai, an American expert on dyskinesia, visited and Professor Li Yongjie signed a book.

  The brave are invincible:

  Let functional neurosurgery blossom in China in 20 years.

  Starting from the first "cell knife" operation 20 years ago, China has established a multi-level and all-round discipline framework of functional neurosurgery, which focuses on dyskinesia, epilepsy surgery and pain, and spreads to neuromuscular spasm and psychosurgery.

  Li Yongjie’s "battlefield for one person" has also become a "team competition".

  At that time, xuanwu hospital established the Beijing Institute of Functional Neurosurgery because of his return, which is the first clinical treatment and scientific research institution in the field of functional neurosurgery in China. Since 2009, it has become the world’s largest "Deep Brain Stimulation Treatment Center", and the number of brain pacemakers implanted has been the first in the world for 10 consecutive years.

  "This is the result of a team competition, but the high technology of the brain stimulator comes from the other side of the ocean. No matter how big the implant is, it just follows, not leads." Li Yongjie is very sober. "It’s my real mission to return to China to start a business, not to be a flash in the pan, but to develop steadily."

  Faced with the huge medical demand and the blank field of functional neurosurgery in China at that time, the doctor with elegant appearance and slow speech showed the well-known word "courage" and shouldered the two burdens of talent training and discipline construction.

  It is hard to imagine that when Li Yongjie cured Zheng Xinyi’s "spastic cerebral palsy" in 2010, brain electrode implantation was still in the early clinical exploration in the world. This means that his frontier exploration will inevitably have the risk of failure.

  Li Yongjie admits that although he "cherishes feathers", he wants to be a good brain surgeon, "focusing on intelligence in the short term, ability in the medium term and responsibility in the long term". To this end, he set a rule for surgery: "I will do the most difficult, latest and risky surgery!"

▲ Professor Li Yongjie performs endoscopic surgery.

▲ Professor Li Yongjie performs endoscopic surgery.

  Once, Li Yongjie met an epileptic with a particularly complicated condition. After she failed in an operation in a foreign country, she was introduced to see a doctor by a medical elder. But after an impeccable craniotomy, her condition actually relapsed. This means that the previous judgment of the lesion is likely to be wrong.

  When Li Yongjie was called to the ward by his colleagues, what he saw was such a scene: the patient’s mother was sitting on the windowsill, desperate. Based on careful observation, Li Yongjie made a decisive second craniotomy and confirmed that the real lesion was in the parietal lobe of the brain, less than 2 cm away from the motor cortex of the brain.

  Do you want to do the third craniotomy? Who will do it? Li Yongjie did not hesitate to stand before the operating table. He carefully removed the focus cells as big as the fingernail, avoiding the dangerous motor cortex injury.

  "The patient is only 16 years old. If he is paralyzed by surgery, the young doctor may not be able to bear this huge psychological burden, then I will come." He smiled and recalled as if those thrilling "moments of life and death" were as usual.

  Dr. Lu Xiaoli, who has been following him, commented that he was "not angry and arrogant" — — "When he is around, everyone relies on him from the heart, which is the personality charm of Professor Li".

  He is honest with others.

  "If you don’t look at it, as long as I pick it up, I must be responsible for the patient to the end." Li Yongjie said, "It must be that those who dare to take responsibility make rapid progress, and those who are afraid of accidents make slow progress. In the end, it is better than taking responsibility."

  "Teacher Li often tells us that being a good doctor is the first priority. For diseases that can be cured, the treatment should be serious and accurate, and the best treatment plan should be discussed for difficult cases. For diseases that have no treatment for the time being, patients and their families should correctly understand and face the disease positively. ‘ Sometimes it’s healing, often it’s helping, always comforting ’ 。” Zhou Changshuai, a student in Li Yongjie, once quoted this sentence to describe his mentor in an article entitled "The Short Story of big doctor".

  More than 100,000 patients from all over the world were diagnosed and treated, and more than 10,000 cases were treated by surgery … … After 20 years, Li Yongjie has realized his ambition of returning to China: 16 "Xuanwu workshops" for hospitals across the country have trained a high-level "national team" of functional neurosurgery and trained thousands of doctors across the country; Cutting-edge technologies such as "cell knife", deep brain stimulation and endoscopic surgery have been introduced into China, and the number of diseases that can be diagnosed and treated has expanded to more than 30.

  "I am obsessive-compulsive disorder and perfectionist." Li Yongjie said, "Scientific research is a kind of spirit, attitude and method. To treat scientific research as work and work as scientific research, we must understand and clarify, run the spirit of scientific research through our work, and constantly expand the scope of application of technology."

  Someone asked Li Yongjie, "Aren’t you afraid to teach your disciples and starve your master?" He laughed: "I have so many new technologies and fields to learn, how can I have time to think about them?"

▲ Professor Li Yongjie is doing popular science propaganda in the column "The Road to Health".

▲ Professor Li Yongjie is doing popular science propaganda in the column "The Road to Health".

  Parkinson’s disease, primary disorder, dystonia, TIC disorder, voluntary movement’s disease, cerebral palsy, myotonia and other motor disorders, various epilepsy diseases, chronic pain such as central pain, peripheral nerve injury pain, cancer pain, visceral pain, soft tissue pain, low back pain, neck and shoulder pain, and neurospinal diseases such as lumbar disc herniation and cervical disc herniation & HELIP; … Experts from Beijing Institute of Functional Neurosurgery have treated or operated on more than 30 diseases recorded in Functional Neurosurgery.

  "In the field of functional neurosurgery, a comprehensive platform for treating diseases like ours can’t be found all over the world." Li Yongjie’s tone is gentle, but he is confident and proud. "In 20 years, I set up a platform for discipline development and brought out a team. Even if I retire, this subject will continue to develop. "

  In the conference room of the Institute of Functional Neurology, picture frames are hung on the wall in order, and each one is longer than the other — — Because this is the annual photo of the Institute.

  "Under the leadership of Director Li, our group photo lasted for 20 years. We are a big family and the team is getting bigger and bigger, so the group photos are getting longer and longer. " Lu Xiaoli said.

  Looking back on the 40 years of reform and opening-up, Li Yongjie was filled with emotion: "We have caught up with the era of reform and opening-up, which is the best and fastest period of economic, social, knowledge, science and technology development in China for thousands of years. From an ignorant teenager to a medical expert and academic leader, from an entrepreneur with dreams to the ideal landing and rooting, my growth and harvest are all thanks to the times. "

  "From an idiotic dream to a dream come true, I am more like the child running on the beautiful beach. Among the sea goods surrounded by waves on the beach, I am delighted to find several colorful shells … … Looking around, there are so many such children! "

  Ten years ago, Li Yongjie wrote this passage with emotion, which is meaningful today.

▲ In 2015, Professor Li Yongjie won the title of "Top Ten Health Guards in the Capital".

▲ In 2015, Professor Li Yongjie won the title of "Top Ten Health Guards in the Capital".

  Always on the road:

  A restless scientist

  Sharpen a sword in 20 years.

  The team of more than 100 people led by Li Yongjie has become the world-famous "China Team" in the field of functional neurosurgery, and ranks among the international "first phalanx" — — Beijing Institute of Functional Neurosurgery was awarded the title of "Clinical Center of Excellence" by international institutions as early as 1999, becoming the only clinical institution in Asia to receive this honor.

  What else does he want?

  "I am a restless person, and I naturally like to do something new and different." There was a childlike look on his face. "I hope to be recognized as a scientist doctor."

  In fact, it was Li Yongjie’s childhood dream to be a scientist, but it was accidental to study medicine.

  In 1960s, he was born in an ordinary family in Datong City, Shanxi Province. In that special time when "sports followed sports", Li Yongjie was a "silent, timid" child because of his family background of "rich peasants", and he was "aged and lonely out of proportion to his age".

  But under his seemingly "juvenile maturity" appearance, there is an interesting and curious soul hidden. He loved natural science since he was a child, and when he was 6 years old, he had a whim to make a perpetual motion machine with water currents and waterwheels. After the Tangshan earthquake, he hung a small hammer with enameled wire and passed through the ring. As long as it shook, it would trigger the ringing of the electric bell. He was very proud of this homemade "seismograph". At the age of 15, he climbed onto the roof to install an antenna, and the self-made "crystal receiver" actually received china national radio’s voice … …

  In 1977, China resumed the national college entrance examination and entered the "scientific spring" with emphasis on education and knowledge.

  "The resumption of the college entrance examination has restored the vitality of the social class." In 1979, Li Yongjie, who won the first prize in Shanxi Physics Competition, gave up the opportunity to attend the university of Shanxi Province without taking the exam and chose to take the college entrance examination, and was admitted to the top 20 in the province. His mother said, "If only our family could have a doctor, you could study medicine", which made him filial and medicine accompany him ever since.

  In 1991, Li Yongjie, who received a doctor’s degree in medicine from Shanxi Medical University and published two English papers in Brain Research magazine, saw the huge gap between domestic and foreign advanced technology. A strong thirst for knowledge made him "desperate" and sold his newly allocated house to study abroad.

  "My growth and harvest are all thanks to the times. If I don’t catch up with the golden age of 40 years of reform and opening up, I may not be able to dominate my own destiny." He said, "Therefore, I firmly believe that my seed will be the home only if it falls on the land of the motherland, and it will grow most vigorously."

  "The door of opportunity opened by reform is getting bigger and bigger, and the chances that individuals can dominate their own destiny are getting higher and higher." Li Yongjie, which chose to return to China, has indeed achieved "the most vigorous growth" — — Under his leadership, Beijing Institute of Functional Neurosurgery keeps track of the latest development of functional encephalopathy in the world, improves technical methods, improves the level of treatment and expands the scope of treatment.

▲ In 1999, Professor Li Yongjie communicated with the Swedish doctor LV-Laitinen, a pioneer of functional neurosurgery.

▲ In 1999, Professor Li Yongjie communicated with the Swedish doctor LV-Laitinen, a pioneer of functional neurosurgery.

  In March 1999, the Institute of Functional Neurosurgery successfully treated Parkinson’s disease with subthalamic nucleus destruction technology, and in the same year, deep brain stimulation technology (brain pacemaker therapy) was developed to treat Parkinson’s disease.

  In May, 1999, the first operation to treat generalized torsion spasm was successful.

  In the second half of 1999, the first operation to treat spastic torticollis, chorea and Tourette’s syndrome was successful one after another.

  In the new century, after creatively expanding the scope of surgical treatment to other dyskinesia diseases, his team began to pay attention to the work in the field of surgical treatment of epilepsy and pain … …

  "Yongjie’s team has always led the development of functional neurosurgery in China, from treating Parkinson’s disease to epilepsy to pain … …” Professor Yuxi Liu of Shanxi Medical University said.

  In the past three years, the average annual operation volume of Beijing Institute of Functional Surgery was over 1,600, and a team with their own strengths and vitality also grew up — —

  Zhang Guojun and Yu Tao focus on the localization of epileptogenic focus and microsurgical treatment of intractable epilepsy; Hu Yongsheng specializes in surgical treatment and nerve regulation of chronic pain; Zhu Hongwei is good at neurospinal and cranial neuropathy; Li Jianyu has 20 years of experience in surgical treatment of dyskinesia … …

▲ Professor Li Yongjie gave a keynote speech at the 2017 Chinese Conference on Functional Neurosurgery.

▲ Professor Li Yongjie gave a keynote speech at the 2017 Chinese Conference on Functional Neurosurgery.

  In September 2017, the Huaxia Conference on Functional Neurosurgery was held in Beijing, and more than 20 top scholars in the world and more than 100 well-known experts in China arrived as scheduled.

  In his speech at the conference, Li Yongjie introduced the summary of the world’s largest surgical cases of dyskinesia completed by the Institute in the past 20 years: a total of 6,467 cases were treated by surgery, and it was also found that the risk of Parkinson’s disease in men was 1.46 times that of women, and the overall dyskinesia was 1.45 times; At the age of onset, half of the patients with Parkinson’s disease developed before the age of 53, and half of them received surgery before the age of 61.

  In the first 10 years after returning to China, Li Yongjie devoted himself to improving the diagnosis and treatment of Parkinson’s disease and epilepsy to the international level, and then he turned his attention to the treatment of chronic pain.

  "The most common and harmful pain is disc herniation. My focus now is how to make it more meticulous and minimally invasive, in line with international concepts and models." He said.

  Exploration is always on the road — —

  "Science, solve ‘ Day ’ The problem; Technology, solve ‘ Land ’ The problem. I am still optimistic about the prospect of surgical treatment of emotional disorders such as major depression, hoping to find that key and open the door to the connection between heaven and earth. " He said.

▲ Professor Li Yongjie spoke at the 10th anniversary celebration of Beijing Institute of Functional Neurosurgery.

▲ Professor Li Yongjie spoke at the 10th anniversary celebration of Beijing Institute of Functional Neurosurgery.

  Li Yongjie, a member of the Standing Committee of the Beijing Municipal Political Consultative Conference, has repeatedly encouraged and called for the reform of the medical system. He has also done his best: in 2014, he promoted social capital to set up the Beijing Xidian Clinic, so that the advanced national specialized medical model can take root and explore a new path of graded diagnosis and treatment.

  "Medical reform has entered the deep water area, which requires not only the skills of those who bow and arrow ‘ Emboldened ’ It requires the sense of responsibility of those involved in medical reform and the courage and responsibility of reformers. The reform of the medical system is risky, and it is even more risky if the medical system is not reformed. Go on the road with responsibility, courage and responsibility, because we believe that after twists and turns and even dangers, we will eventually reap glory. " Li Yongjie’s words spoke out the common aspiration of the participants in the western clinic.

  "Every discipline has its scientific, systematic and complete requirements and development expectations … … As far as I am concerned, more than 20 years of study, research, practice and teaching experience in the field of functional neurosurgery are even more eager for it. " In 2018, Li Yongjie led the team to compile the lifelong learning and practice into a 1.5-million-word masterpiece Functional Neurosurgery. "The editorial team adheres to the concept of combining theoretical interpretation with clinical practice, and hopes to weave a whole picture in the field of functional neurosurgery with this context, hoping that it will become a classic in the field of functional neurosurgery."

  "Patients with functional diseases of the nervous system account for more than 10% of the total population, and there are tens of millions of people who need interventional therapy. The number of people who can benefit from surgery is conservatively estimated to be as high as 5 million, which is about 10 times that of patients with brain tumors. Such a huge demand for medical services cannot be ignored, and historic opportunities for discipline development should not be missed. " He appealed in the preface.

  In October 2017, Zhu Hongwei and Zhang Jiaxing of Beijing Institute of Functional Neurosurgery participated in an important international academic conference in neurosurgery, and found that this conference "no matter the lecture content or the frontier field display, the function and nerve spine account for nearly half, and everyone is working hard on stereotactic, navigation and artificial intelligence … …”

  "This conference really shows the future development direction of neurosurgery, from which we can see our shortcomings and our status. It is proud that many of the work of the Beijing Institute of Functional Neurosurgery is at the forefront of the world. I believe that in new fields, we will also keep up with the international pace and make our own characteristics in the field of neurospinal surgery. " Zhang Jiaxing said.

▲ Playing basketball is Li Yongjie's favorite sport.

▲ Playing basketball is Li Yongjie’s favorite sport.

  In the face of achievements, Li Yongjie was unusually sober.

  "We let the international advanced technology take root and bear fruit in China, and even ran away with international counterparts in clinic. Of course, there is innovation in this, but deep brain stimulation technology was invented abroad, and we still lack real original inventions. We need to open up new fields and invent new equipment, and start with creativity, research and development, market development and resource integration to establish a complete chain of scientific research and industrial development. " Li Yongjie said, "From quantitative change to qualitative change, this possibility has greatly increased now."

  Li Yongjie revealed that his team is brewing non-invasive surgery. "This is the next step in surgery and treatment, and it will be a big breakthrough. I am optimistic about it."

  On the occasion of Functional Neurosurgery in Fu Zi, it was the time when Alpha Go defeated the top human Weiqi players.

  "The brain has 60 billion to 70 billion brain cells. If you regard them as planets, then the brain is as infinite as the universe." Li Yongjie, who is optimistic about brain-computer interface, said excitedly that if we can join hands with engineers, it may connect human imagination and mobility. "That will open up a new world of functional neurosurgery".

Chinese modernization brings new opportunities to the world with the new development of China.

  "Thanks to friends from China who came to Wan Li to invest and build factories here, and built a bridge to prosperity for us." In the Oriental Industrial Park in Dukam, Ethiopia, hundreds of local employees are concentrating on their work on the assembly line.

  In recent years, Oriental Industrial Park has witnessed the in-depth development of pragmatic cooperation between China and Ethiopia, and has also created a large number of jobs for the local area. In addition to the Oriental Industrial Park, there are more than 10 industrial parks invested or built by China in Ethiopia. These industrial parks play a huge role in expanding local employment and helping economic transformation, and are increasingly welcomed by local people.

  Different from the modernization in which some established capitalist countries violently plundered colonies at the expense of other countries’ backwardness, Chinese modernization emphasizes mutual benefit and win-win with all countries in the world, promotes the building of a community of human destiny, and strives to contribute to human peace and development.

  The Chinese-style modernization road provides a brand-new choice for countries and nations in the world who want to speed up their development and maintain their independence.

  △ On August 31st, 2022, the first China-Laos Railway international freight train in Fujian departed from Jiangyin Port Station in Fuzhou.

  On August 31st, a China-Laos Railway international freight train loaded with tea, fertilizer and other raw materials left Jiangyin Port Station in Fuzhou, China for Vientiane, Laos. Fujian started the first China-Laos Railway international freight train.

  In 2015, General Secretary of the Supreme Leader, together with Lao leaders, made a major decision to jointly build China-Laos Railway. Six years later, a 1035-kilometer modern railway turned the natural moat into a thoroughfare, and Laos realized its dream of changing from a "land lock country" to a "land link country".

  "China was not the first to say that he would come to Laos to repair the railway, but he was the only one who actually came to Laos to repair the railway." In the face of great changes, the Lao people are filled with emotion.

  In the autumn of 2013, the Chairman of the Supreme Leader proposed to jointly build the Belt and Road Initiative. After nine years of hard work, we have made solid and heavy achievements in building the "Belt and Road" — — The railway dream of the Lao people has come true, Cambodia has entered the "highway era", Maldives has a cross-sea bridge, Belarus has its own car manufacturing industry, and Africa has an electrified railway and light rail … …

  The Belt and Road Initiative originated in China, but the opportunities and achievements belong to the world.

  △ On December 17th, 2020, in East Highland Province, Papua New Guinea, local people who participated in the 9th training course of China’s technical project of assisting Papua New Guinea’s grass and upland rice graduated.

  In East Highland Province of Papua New Guinea, housewife Zaka Aboli only planted mushrooms in 2020, earning 15,000 kinas, about 27,000 yuan, more than 10 times higher than traditional coffee and vegetables.

  In the local area, the fungus grass from China is a household name: it can be used not only to grow mushrooms, but also to improve the ecology, and is regarded as "divine grass" by local farmers. Many people give their children the name of "fungus grass".

  At the third symposium on the construction of the "Belt and Road", General Secretary of the Supreme Leader recalled a past event more than 20 years ago. During his work in Fujian, the Supreme Leader received the visiting Governor of East Highland Province of Papua New Guinea, Rafanama. "I introduced him to the fungus technology, and the governor was very interested in it. I sent Lin Zhanxi from Minning Town. "

  General Secretary of the Supreme Leader said: "After I became the vice president of the country, I will continue to promote fungus in South Pacific, Africa and South America. Now this technology has taken root in more than 100 countries and created hundreds of thousands of jobs for the local area. "

  The "Belt and Road" has become the most extensive and largest international cooperation platform in the world today. 149 countries and 32 international organizations signed more than 200 cooperation documents with China to jointly build the "Belt and Road", and a large number of pragmatic cooperation projects were accelerated, which promoted economic development and benefited people’s livelihood and welfare.

  Data show that from 2013 to 2021, the accumulated trade volume of goods between China and countries along the Belt and Road was nearly 11 trillion US dollars, and the two-way investment exceeded 230 billion US dollars. Pascal lamy, former Director-General of the World Trade Organization, believes that globalization is facing various problems and challenges, and the "Belt and Road Initiative" proposed by China will become the engine of globalization.

  "At first, I took part in China International Import Expo(CIIE) with a try attitude, but I was deeply shocked by the scene. The opportunity of China’s big market is so vivid. " This year, the German Short Group signed up for the 5th China International Import Expo(CIIE).

  With the introduction of high-end production lines, the establishment of medical glass tube factories and the establishment of R&D centers in the Asia-Pacific region, Schott’s booth area has expanded fivefold after more than four years of traveling with Bo Jin, and at the same time, he has expanded his confidence in China’s opening opportunities.

  "Economic globalization is an irreversible historical trend" "China’s market is so big, everyone is welcome to see it" "The general trend of countries moving towards openness and cooperation has not changed" "China is willing to work with other countries to build an open world economy and let the open spring breeze warm the world" … … For four consecutive years, the Chairman of the Supreme Leader delivered a keynote speech at the opening ceremony in China International Import Expo(CIIE), injecting positive energy of openness and cooperation into the world.

  △ On August 30th, 2022, the 5th China International Import Expo(CIIE) Food and Agricultural Products Exhibition Area, Medical Devices and Medical Care Exhibition Area was held at the National Convention and Exhibition Center (Shanghai).

  On September 29th, China International Import Expo(CIIE) "6 days +365 days" displayed the trading service platform all the year round — — Shanghai International Friendship City Port was officially unveiled. This new platform not only injects "fresh blood" into China International Import Expo(CIIE), but also enjoys the relevant convenience and preferential measures of China International Import Expo(CIIE).

  "In an external environment full of uncertainties, the fifth China International Import Expo(CIIE) will definitely be held offline as scheduled. This certainty has convinced the world of China’s confidence and determination to share development with the world." Pang Bide, Chief Financial Officer of L ‘Oré al Group in North Asia and China, Chairman of China International Import Expo(CIIE) Exhibitors’ Union, said.

  According to statistics, the first four China International Import Expo(CIIE) exhibitors released more than 1,500 new products, technologies and services, and the cumulative intentional turnover reached more than 270 billion US dollars.

  China’s open door will not be closed, but will only get wider and wider.

  △ According to the data of China Customs, the trade volume between China and RCEP member countries increased by 5.6% from January to June this year, which highlighted the pulling effect of RCEP on all parties’ trade. The picture shows the Qingdao area of Shandong Pilot Free Trade Zone.

  Promulgating and implementing the foreign investment law and reducing the negative list of foreign investment access for five consecutive years; Promote the formal entry into force of the Regional Comprehensive Economic Partnership Agreement, the world’s largest free trade agreement, and actively apply to join the Comprehensive and Progressive Trans-Pacific Partnership Agreement; The number of pilot free trade zones has been expanded to 21, and 278 institutional innovations have been formed and promoted to the whole country or specific regions … … In the past ten years, we have unswervingly implemented a high-level opening to the outside world, and a new pattern of all-round, multi-level and wide-ranging opening-up has been accelerated.

  Evandro Carvalho, a professor of law at the Vargas Foundation in Brazil and a well-known expert on China, said: "China has successfully opened up a Chinese modernization road, which is beyond the western modernization road."

  Martin jacques, a British scholar, believes that China provides a "new possibility" and opens up a new road of civilized development with win-win cooperation, joint construction and sharing. "This is a great pioneering work that has never been done before, and it is also a great creation that changes the world."

  The road of Chinese modernization is getting wider and wider, which not only develops itself better, but also benefits the world more.

  "With peace, the country can prosper; With rain and dew, the earth can prosper. "In September this year, when the Chairman of the Supreme Leader attended the 22nd meeting of the Council of Heads of State of the member States of the Shanghai Cooperation Organization, he quoted Uzbek proverbs and profoundly stated that it is the common pursuit of all mankind to take the road of peaceful development.

  Recently, the 2022 "International Youth Tour to China" came to Qingdao, Shandong Province. Young people from 10 countries walked into Qingdao Port, Shanghe Demonstration Zone and other places in Shandong to learn about the SCO’s international cooperation and innovation model.

  "The SCO has created many institutionalized youth exchange programs, allowing young people from different countries to learn from each other and build a broad stage for youth exchanges and cooperation. Nepal is a dialogue partner of the SCO. I am fortunate to be able to participate in these projects and promote the development of youth in learning and communication. " Lili, a Nepalese girl, has been studying and working in China for more than 7 years, and obtained a doctorate. In 2019, Lili joined the Kathmandu Center of SCO Youth Platform (SCOLAR) and cooperated with Nepalese universities to provide entrepreneurial advice and guidance to local youth within the framework of SCO to help them realize their entrepreneurial dreams.

  He went to China for 16 times, completed more than 530 interventional operations, and cured more than 600 children with congenital heart disease. In Kyrgyzstan, Wang Zhen, a doctor from, is known as the "God of Children’s Rescue".

  A photo of a dozen children and their parents in front of the National Heart Hospital of Kyrgyzstan has been treasured by Wang Zhen for many years. These are the children who have been treated by him. Everyone signed their names on the back of the photos and gave them to Wang Zhen solemnly to express their gratitude. "It is our unshirkable responsibility to share medical experience and technology with regional countries." Over the years, Wang Zhen has received many commendations, but he said that the most precious recognition is the smiling faces of children.

  △ In January, 2022, China’s aid to Tonga, prepared by China-Pacific Island Emergency Material Reserve (Guangdong), was assembled in Guangzhou and transported to Tonga.

  In the face of the epidemic in the century, China has provided hundreds of billions of anti-epidemic materials to 153 countries and 15 international organizations, and more than 2.2 billion doses of vaccines to more than 120 countries and international organizations. "A thousand miles to send a sheep, deep friendship" and "True feelings are all in tea" are vivid portrayal of China’s mutual help and joint efforts to fight the epidemic.

  In January this year, the volcano in Tonga, a Pacific island country, erupted and caused tsunami, volcanic ash and other disasters. Boxes of relief materials with the words "All countries are brothers, Wan Li rises on the same day" were transported from China to Tonga. Pakistan suffered a rare flood this year, and China quickly put materials into the front line of disaster relief, and sent an expert group to provide assistance to Pakistan’s flood control and disaster relief work within its capacity … …

  In the decade of the new era, China put forward important ideas such as building a new type of international relations and building a community of human destiny, and important initiatives such as global development initiative and global security initiative to promote the common values of all mankind, such as peace, development, fairness, justice, democracy and freedom, and lead the trend of human progress.

  △ On February 20, 2022, the fireworks display at the closing ceremony of the 2022 Beijing Winter Olympics was "One under the World".

  The greatest significance of China’s peaceful development to the world lies not only in making one fifth of the world’s population rich, but also in the new road of Chinese modernization created by China, which has expanded the way for developing countries to modernize.

  With its own practical actions, China has always kept its promise of "being a builder of world peace, a contributor to global development, a defender of international order and a provider of public goods", and made unremitting efforts to realize the sustainable and peaceful development of the world and promote the building of a community of human destiny.

  Chief Producer Qian Wei Wang Shanshan

  Producer: Ou Zhang

  Producer Xing Lai

  Editor-in-Chief Ning Lili

  Editor Yang Caiyun

  Visual sense Jiang yuhang

  Proofread Cheng Yu

The Chinese team won the mixed doubles championship and runner-up, IVECO will take you to witness

  On August 5, 2018, the mixed doubles final of the Nanjing World Championships came to an end. Chinese duo Zheng Siwei and Huang Yaqiong defeated teammates Wang Yilu and Huang Dongping 2-0 to win the championship.
   
  In the previous competition, Wang Yilu and Huang Dongping lightly defeated a pair of Hong Kong players, and met their teammates Zheng Sixi and Huang Yaqiong in the mixed doubles final early, and won the mixed doubles championship and runner-up in the Chinese team in advance. With full firepower on the court and full strength off the court, IVECO, as the official designated car of the 2018 World Badminton Championships, carried the task of escorting the event.
   
  The natural strong are not small, and the strong are always strong.
   
  This is the Chinese badminton player won the mixed doubles championship again after a lapse of three years. In the history of the World Badminton Championships, our country’s players have won the championship eight times, four of which have won the championship and runner-up trophy.

Autohome
   
  This competition is not only an opportunity for Chinese players to prove their strength, but also a process in which the natural powerhouses constantly challenge themselves.
   
  It is understood that since the official listing at the end of last year, the new generation of IVECO Wolfson has won the excellent reputation of the industry and the market, and won the "VAN of the Year in China 2018" with all-round excellent quality, the "Top Ten Light Buses" for the 60th Anniversary of China’s Bus Industry, the 2018 China Truck Extreme Challenge "Ice and Snow Extreme Truck", and the "Consumer’s Favorite Commercial Vehicle" in the China Automobile Consumer List and other industry blockbuster honorary awards, and the quality and performance have been fully recognized and affirmed.
   
  Through its rich experience and stable quality, IVECO has proven to the world that the strong are always strong.
   
  Born strong, we are different, brand new
   
  The two pairs of players in this derby battle, Zheng Sixi, Huang Yaqiong, Wang Yilu and Huang Dongping, are also the top two seeded combinations of this world championship. The two sides have played against each other four times before in the competition, of which Zheng Sixi and Huang Yaqiong maintained a complete victory and occupied an absolute advantage.

Autohome
   
  Outside the arena, on the road to the world championship, the new IVECO also reflects the outstanding quality of the natural powerhouse.
   
  In the protection of this badminton world championship, IVECO has demonstrated its all-round strength in power, design, intelligence, handling and safety, justifying IVECO’s strong reputation with comprehensive advantages.
   
  In terms of power, the new generation of IVECO Wolfson is equipped with the F1 series of high-efficiency platinum power, F1A and F1C two sets of power systems with great performance, matching 59 basic models. The 2.3L F1A engine has a power of 90KW and a maximum torque of 320N.m, and the 3.0L F1C engine has a power of 107KW and a maximum torque of 370N.m. Powerful, fast and ruthless.

Autohome
   
  The new generation of Iveco Wolfson vehicle adopts a C-section strong frame stringer structure, a unique one-piece rear axle and a double fork arm transverse leaf spring independent suspension, all of which adopt a lightweight and high-strength design. The newly developed 4350mm wheelbase model has a cargo space of up to 16.7 cubic meters. With a high-strength and sturdy frame, the maximum total weight reaches 7 tons.
   
  In terms of intelligence, the intelligent central control visual system, equipped with a 3.5-inch multi-function TFT display screen, can provide real-time information for the vehicle. The CAN BUS vehicle management system separates the power network (engine ECU, ESP, etc.) from the comfort network (air conditioning, audio, etc.), and connects the vehicle OBD interface with the vehicle fault diagnosis instrument to realize visual fault diagnosis. Through the GSI shift prompt function, intelligent start and stop, intelligent power management, automatic air conditioning and other systems, the vehicle condition intelligence response mechanism enhances vehicle safety and reliability, and provides users with excellent performance suggestions.
   
  In terms of vehicle handling, the new generation of Iveco Wolfson vehicles are designed using ergonomic principles. The adjustable multi-function steering wheel has a diameter of only 390mm, with adjustable height, simple control and smooth driving; the new multi-mode air suspension, one-button operation, convenient and fast, can maneuver to adjust the height of the body according to the road and load conditions to improve the high-speed stability and ride comfort of the vehicle. Easy to control and flexible.

Autohome
   
  In terms of safety, Wolfson excels. The lane departure warning system LDWS can detect the unintentional lane change of the vehicle. When the vehicle is in a high-speed steering state and the turn signal is not lit, the warning function is automatically activated, and the alarm sound is automatically issued through the Control Unit to remind the driver to pay attention to safety. In terms of braking, the Power Plus ventilated disc braking system with better heat decay resistance is adopted, and the rear brake adopts a row-in-one caliper, which has the function of automatic adjustment of parking clearance. All systems are equipped with BOSCH version 9.0 ABS brake anti-lock braking system as standard. With the EBD electronic braking force distribution system, the vehicle can be avoided from losing control during emergency braking, which increases the braking efficiency of the whole vehicle by 27%. TPMS active tire pressure warning system actively monitors tire pressure and temperature, and uses advanced and effective safety management system to ensure the safety of people and goods.
   
  Winning the World Badminton Championship is just a new beginning on the road to victory. There are still bigger challenges ahead for the Chinese badminton team to conquer. Let’s work with IVECO to wish the Chinese athletes victory!
   
  It is reported that in 2018, Nanjing IVECO will also launch a new generation of IVECO OSHENG new energy, 8AT, coach and other new models. Among them, the new generation of IVECO OSHENG 8AT models are planned to be newly unveiled during the Beijing RV Show in September and officially launched at the Guangzhou Auto Show in November.

Suzhou Maybach S-class price reduction news! The highest discount 60,000, act quickly

Welcome to Autohome Suzhou Promotion Channel, we bring you exciting news! At present, the high-profile luxury car is conducting an unprecedented promotion in Suzhou area. Buyers can enjoy generous discounts of up to 60,000 yuan, making this top luxury car that originally started at a price of up to 1.408 million, now has a price at their fingertips. Take this rare opportunity and click "Chatti Car Price" in the quotation form to make your car purchase dream come true in front of actual discounts. Don’t miss it, take action now!

苏州迈巴赫S级降价消息!最高优惠6万,赶快行动

The Maybach S-Class is a model of luxury cars, and its exterior design highlights unparalleled dignity and elegance. The front face is made of the Maybach family’s unique straight waterfall air intake grille, and each chrome trim is like a carefully woven luxurious mesh, exuding a low-key and luxurious temperament. The body lines are smooth and the proportions are coordinated, and the overall style shows the perfect combination of classic and modern, and the details are full of luxury and refinement. Whether it is the sculptural sense of the front of the car or the elegant curve of the body, it makes people recognize its noble identity at a glance.

苏州迈巴赫S级降价消息!最高优惠6万,赶快行动

The Maybach S-Class is an example of a luxury sedan with its elegant body proportions and refined design. The body size is 5470mm*1921mm*1510mm, and the wheelbase is up to 3396 mm, ensuring a spacious and comfortable interior space. With a front track of 1655mm and a rear track of 1683mm, this reasonable layout not only enhances driving stability, but also makes the vehicle visually more balanced. The tire size is 255/45 R19, and the front and rear wheels are matched with atmospheric wheel design, highlighting its combination of luxury and dynamics. The smooth side lines fully demonstrate the noble temperament and engineering precision of the Maybach S-Class.

苏州迈巴赫S级降价消息!最高优惠6万,赶快行动

The Maybach S-Class interior design shows the perfect combination of luxury and sophistication. The luxury steering wheel made of high-grade leather material, its electric up and down + front and rear adjustment functions ensure the driver’s comfort. The 12.8-inch central control screen is not only considerable in size, but also equipped with an advanced automatic speech recognition control system, which supports functions such as multimedia, navigation, phone and air conditioning, providing the driver with a convenient and intelligent experience. The seat part, whether it is the driver’s seat or the passenger’s seat, is equipped with multi-directional electric adjustment, including front and rear, backrest, high and low, leg rest and waist support, ensuring that the occupant can enjoy the ultimate comfort. Whether it is the heating and ventilation function in the front row, or the memory of the electric seat and the leg adjustment in the rear row, Maybach’s attention to detail and commitment are all reflected.

苏州迈巴赫S级降价消息!最高优惠6万,赶快行动

The Maybach S-Class is powered by a powerful 3.0T turbocharged engine with a maximum power of 280 kilowatts and an excellent output. This engine is capable of delivering 500 Nm of peak torque, which drives the vehicle to easily handle various road conditions. It is matched with a 9-speed automatic transmission, which ensures smooth power transmission and ease of driving.

Summarizing the evaluation of the owner, Maybach S-Class won his appreciation with its atmospheric and solemn overall design and exquisite and elegant details. As he said, "Whether it is the smooth lines of the body or the domineering front face, I feel the unique charm of Maybach." The exterior design of this car undoubtedly surpassed its kind in the heart of @struggle or hard work, and became the best in his heart. Every time he saw it, he was filled with pride and satisfaction. For drivers who pursue high quality and unique aesthetics, Maybach S-Class is undoubtedly a trustworthy and choice luxury car.

Nongfu Spring is not as good as tap water?

  On the one hand, China Resources Yibao encountered a PH test strip, and on the other hand, Nongfu Spring was accused of being "not as good as tap water". The "two bottles of water" with growing grievances finally broke out in a full-scale "water battle" at the turn of this spring and summer. Recently, the war of words and words between the two sides is not enough, and the next battle will be in court.

  Nongfu Spring is negative and frequent, blame Yibao

  In the past month, Nongfu Spring has been exposed to mildew in bottled natural water, black unknown objects, brown floating objects, garbage siege in the water source, and different colors of the same batch of products. On April 10, another "industry insider" broke the news that Nongfu Spring’s standard is not as good as tap water.

  This series of quality disturbances has raised questions about Nongfu Spring. On April 11, Nongfu Spring finally couldn’t help but jump out and issue a statement, directly accusing the series of reports against Nongfu Spring of being deliberately planned, hidden behind the scenes is the state-controlled drinking water company, China Resources Yibao. In fact, when the water source of Nongfu Spring was exposed to garbage siege, Nongfu Spring pointed out that "this matter was done by a competitor", but did not directly name the competitor at that time.

  Observing the series ** publicity actions ** Yibao in recent times, it seems that there is "suspicion". After March 15 this year, China Resources Yibao once cooperated with a large portal website to launch the special topic ** "The Sadness ** Drinking Water in China", and published the same content advertisement in elevators and other channels. It listed all the water pollution incidents in China in the past 10 years, and then pointed out that "Do you still dare to drink the water transported by nature?" The target pointed to the well-known Nongfu ****** advertising slogan – "Nature’s Porter". The relevant website has now removed the topic. Since then, in the process ** Nongfu ****** being exposed to the pollution problem ** the water source ** the Danjiangkou, the figure ** China Resources Yibao has also emerged. On April 9, Yibao held a press conference in *******, the main content ** which was the responsibility ** drinking water enterprises to protect water sources and the need for water sources to meet drinking water standards.

  In its statement, Nongfu Spring also listed "criminal evidence" of Yibao, as competitors in Hunan, Guangdong, Sichuan, Chongqing, Hubei and other places have hired people to distribute leaflets attacking Nongfu Spring to retail stores and consumers door-to-door.

  More interestingly, there was a speculation circulating in the industry that Nongfu Spring’s recent troubles were similar to the way it had attacked its competitors in the past. Coincidentally, one of Nongfu Spring’s executives had moved to China Resources Yibao…

  However, Li Kai, the marketing director of China Resources Yibao, told reporters that he denied all kinds of speculation from the outside world, saying that the company would not do anything that violates fair competition.

  Yibao retorted, and a scolding war broke out

  Nongfu Spring has set off the climax of this round of war of words since the 11th, and released 17 long Weibo in a row in just 6 days from the 11th to the 16th.

  Moreover, Nongfu Spring is not satisfied with the theory of "naming", but also poses a posture of death and destruction. The official Weibo of Nongfu Spring has publicly recruited no less than 5,000 people, "to go to Bunongfu Spring and China Resources Yibao, which uses tap water as its water source, to compare the quality of all water sources, factories and products."

  Citizen Mr. Liu told reporters that he had forwarded the above-mentioned Weibo and had received a private message invitation from the official Weibo of Nongfu Spring on the 16th.

  This move made China Resources Yibao furious. At 1 noon on April 12, the official Weibo of China Resources Yibao posted a message: "People are not sages, who can be wrong! If you can change it, you can’t be good. ‘This is the case in life, and even more so in business! Advise a certain enterprise to be responsible to consumers and have the courage to take responsibility. Instead of the disaster moving eastward and grabbing the disaster on others!" Weibo. Although this Weibo did not specify the target, it was unanimously regarded by the outside world as a call to Nongfu Spring.

  In fact, China Resources Yibao has been holding back its breath for a long time. On March 22 this year, "International Water Day", Nongfu Spring was witnessed to do a demonstration of the pH value of bottled water at several major subway entrances in Guangzhou, and the bottled water for consumers to compare was Yibao. In the consumer sourcing activity held by Nongfu Spring every year, Yibao was also present at the pH value test site of different brands to be demonstrated by the example sign.

  "Yibao has always been annoyed by the practice of testing Nongfu Spring Water, and it is not impossible to fight back for this matter," a person close to Yibao told reporters. Regarding the recent statement of Nongfu Spring, the relevant person in charge of China Resources Yibao said that this is the usual method of Nongfu Spring. Once there is negative news, it depends on competitors, and before Wahaha and Master Kang. However, the person did not respond positively to Nongfu Spring’s suggestion that consumers were invited to visit the Yibao factory.

  After being ridiculed by the official Weibo of China Resources Yibao, the official Weibo of Nongfu Spring quickly responded: "As a state-owned holding enterprise and a listed company, if China Resources Yibao dares to do it, it must dare to admit it, and maintain the moral bottom line of the enterprise in the hearts of the people. Don’t have the courage to do it, but don’t have the courage to admit it." And used a long Weibo to post a batch of online screenshots, leaflets and other pictures to prove that the series of incidents encountered by the company were carried out by China Resources Yibao.

  Since then, the public war between the two major bottled water giants in China has intensified.

  Yibao sued Nongfu Spring for reputation infringement

  On April 13, China Resources Yibao released an open letter to all China Resources Yibao people, in which it stated that for the deliberate attacks of certain companies, the company will retaliate or use legal weapons to protect itself when appropriate, and also ask employees not to go into muddy waters.

  On the same day, the media reporters received a "100,000 whys of Nongfu Spring" from the marketing director of Yibao: It is said that Qiandao Lake is the tap water source of Chun’an County, Danjiangkou is the tap water source of Danjiangkou citizens, and Wanlv Lake is the power source of Guangdong Xinfengjiang Hydropower Station. What kind of water source is Nongfu Spring? The water sources of Nongfu Spring are deep lake water, deep reservoir water, self-swimming spring, mountain spring water, groundwater… No matter what kind of water, it implements the local standard of natural water in Zhejiang Province. May I ask why? Yibao implements the national unified standard no matter where it is produced. May I ask Nongfu Spring, how can you feel?!

  In this regard, Nongfu Spring said it was "ridiculous", and the quality of Nongfu Spring was much higher than national standards, industry standards and local standards.

  Facts have proved that China Resources Yibao did what it said. On the afternoon of the 16th, China Resources Yibao confirmed in a notice to reporters that the company had filed a lawsuit against Nongfu Spring with the People’s Court of Nanshan District, Shenzhen, which was officially accepted by the court on April 15, 2013.

  The report said that recently, through its official Weibo, Nongfu Spring has claimed that the relevant reports of its own product quality problems recently disclosed by the media are deliberately planned by China Resources Yibao, and that China Resources Yibao uses the public’s panic about food safety and environmental pollution as a marketing tool.

  "The above false statements have not only been widely reposted through social media, but have also been continuously reported by major mainstream media and portal websites across the country, causing serious damage to China Resources Yibao’s reputation, business reputation and commodity reputation." Yibao said that according to the provisions of the civil law, it believes that Nongfu Spring’s behavior has constituted an infringement of China Resources Yibao’s reputation rights and should bear the legal liability for infringement according to law.

  The notice said that it believes in the public and the law will give Yibao a "just result", adding that any company’s actions to infringe on the reputation of competitors will not be successful, and it is not allowed by law. The notice reiterated that the company has firmly opposed, is and will not use illegal means to participate in market competition.

  As of press time, Nongfu Spring’s spokesperson, Mr. Wu, had not responded to the company’s lawsuit against China Resources Yibao, or even did not answer the phone. The official Weibo of Nongfu Spring, which has issued frequent statements to the public in recent days, also said nothing about this.

  Nongfu Spring pinched his peers and pinched the media

  The reporter noticed that since China Resources Yibao issued an open letter to take up legal weapons, the focus ** public opinion on Nongfu ****** has begun to shift. Nongfu ******’s subsequent statements did not name names and China Resources Yibao, but focused on clarifying water quality standards. Instead, they were pinned on the ******* Times.

  The **ficial Weibo ** Nongfu ****** has published several water quality monitoring reports, and the ******* Times, which has repeatedly "named" and questioned its water safety, even released a harsh message on Weibo on the 15th: "You can’t run away, and don’t even think about running."

  In response, "******* Times **ficial Weibo" posted a response on the morning ** the 16th, "In front ** the standard, you can’t run away, and don’t even think about running away." Since the dispute over product standards appeared in the newspapers, Nongfu ****** first accused competitors ** smearing, and then cursed the media for ignorance, but refused to give a tenable reason on the standard issue. Instead, he avoided the reality and repeatedly emphasized that "product quality" is higher than the national standard.

  Subsequently, the **ficial Weibo ** Nongfu ****** issued a "four-fold" ******* Times "Weibo, and posted a" Fourth Statement ** Nongfu ****** "signed on April 16 in the form ** a long Weibo. The content said:" Nongfu ****** products are comprehensively better than GB5749-2006 national tap water standards, ** which 21 indicators are 12-1000 times better than the national standard. Nongfu ****** compared with a full set ** 106 test indicators and 31 internal control indicators, a total ** 137 test reports were fully released. We hope that after the ******* Times sees the test report, should it feel, is your journalistic moral conscience still there? " Nongfu ****** insists that the quality ** the product is higher than any existing drinking water standards in the country, and it is also better than the current tap water standards. The arsenic and cadmium levels in the product are below the detection limit, and the levels are too low to be detected. Mold and yeast are also not detected.

  The Beijing Times V17 published two blogs in a row: one is "to be more serious about water standards and pay attention to the right to health"; the other is "I don’t know why Nongfu Spring doesn’t cooperate with normal interviews?!" The Beijing Times pressed Nongfu Spring: Why did companies abandon higher national standards with universal significance and choose lower local standards?

  At the same time, it was disclosed that the reporter contacted Wu Chaochao, a staff member of the Media Department of Nongfu Spring, and sent an interview outline as required. After that, he repeatedly dialed his phone, but the other party did not answer and did not receive any response.

  Our reporter found that since April 16, Wu Chaochao, who is responsible for media communication, has not answered the reporters’ calls.

  Southern Daily reporters, Zhou Zhao and Zhao Binghui

  Reporter observation

  Don’t pretend to be an ostrich in case of trouble in Nongfu Spring

  Pretending to be an ostrich and burying your head in the sand can only deceive yourself. However, it is impossible for you not to look up, open your eyes, or face the objective world for the rest of your life. The problem has to be solved. When everyone pays attention to you, they all prick up their ears and wait to hear your explanation. You don’t want a good opportunity to clarify. When you wait for your spirit to practice your lines and plan to give a speech, I am afraid that there will be no interested audience.

  Nongfu Spring released five test data on total arsenic, cadmium, selenium, nitrate and bromate in bottled water produced by multiple factories on the 14th. However, from the response, Nongfu Spring only said in general that "third-party testing agencies provide testing data." As for who the "third party" is, Nongfu Spring has not made it public. According to media reports, Nongfu Spring has commissioned the Hangzhou Quality and Technical Supervision and Testing Institute to test its products, but the test data is significantly different from the data released by Nongfu Spring on the 14th. Such an important test, but not telling which agency tested it, will inevitably weaken the persuasiveness of its data. You sell drinking water, not train tickets, and you can’t say "believe it or not, I believe it" to consumers across the country and send people away.

  A responsible enterprise should strictly implement national, local, and relevant industry standards, even the most stringent one, and at the same time mark the product packaging as required. Since Nongfu Spring’s products are of high quality, leaving behind the national standard eight streets, why not mark the national standard on the product packaging generously? There is no need to choose a place with the lowest requirements and post the standard everywhere to attract people’s dislike.

  Enterprises can’t just talk about being responsible to consumers. In action, they must first take consumers seriously and answer every question of "God" seriously and sincerely.

  Zhou Zhao

(Source: Southern Daily)

Sales have plummeted by nearly 40%, and NIO’s hope of turning around is already slim?

On May 1, NIO announced its sales for April. The domestic leading new force only delivered 6,658 new cars in April, a decrease of nearly 40% compared to March. In contrast, 25,681 new cars were sold at the same average price above 330,000, and 8,101 new cars were sold at JK. That is to say, NIO is not only no longer the top seller of new forces, but even failed miserably in the battle at the same price.

In early April, Li Bin said in an interview that if this year’s work is not good, 24 years will become another 19 years, that is, NIO may have to "return" to the ICU again. Judging from the current situation, this time may be further advanced.

What was the problem with NIO? Why did the new power, which was still in full swing in the past two years, suddenly fall into crisis? Let Kung Fu Car take everyone to take a look.

(1) The more models are sold, the fewer cars are sold

NIO has never been a brand that takes volume. As early as 2014, when the NIO brand was established, the slogan shouted was to represent domestic high-end electric vehicles to participate in global competition. But if there is no volume at all, the brand will be difficult to survive.

In December 2017, ES8 was launched, ES6 was launched in December 2018, and EC6 was launched in July 2020. NIO has completed the preliminary product layout. The three cars together can contribute about 10,000 units of sales per month, which was very moist at that time.

What’s more impressive is that NIO has "almost" achieved its goal. As an independent brand, its average transaction price exceeds 400,000 yuan, which is comparable to Mercedes-Benz and BMW, and far exceeds Audi. This result is also very scary. You know, this is a brand that has only been born for a few years, and it can be said that the sky is its limit.

But NIO’s subsequent performance was a big surprise. Since 2021, NIO’s new speed has accelerated significantly. ET7, ES7, ET5, EC7 have been listed successively, and old models such as ES6 and ES8 have also been rejuvenated. As a new force, NIO has seven models on sale simultaneously, but the monthly sales are only poor more than 6,000, which is very disappointing. As a comparison, the ideal three cars sell more than 20,000 per month, and the Tengshi (Parameter Shu Picture) sells more than 10,000 a car, and the polar krypton single model sells more than 8,000.

In the case of such a fragile brand, the "car sea tactics" are enough to show that NIO is casual in product definition. I talked to a former NIO engineer before, and he said that NIO’s approach is that the supervisor swings his arm and has no brains to start.

There is no clear definition before the project starts, and then there are more and more problems, and finally it is a work in progress or marginalized product when it is delivered to the market.

This approach will work in the "early days of entrepreneurship" in the future. For example, when ES8 first came out, although many functions were not opened. But because there are not many decent competitors at the same price, it sells well. But at this moment, in today’s highly invaded market, it is undoubtedly a great waste of resources to push new ones at will.

ET7, as a flagship sedan, is a front-drive platform, and ET5, as an entry-level model, is a rear-drive platform. The non-flagship ES7 entered the second-generation platform and lidar early, killing the "aging" ES8 in one fell swoop, but there is no market at all because of pricing issues. Such a slapstick operation is not uncommon here at NIO.

There is a saying that Li Bin and Qin Lihong are both liberal arts students, which makes them often do not make careful inferences and reviews when it comes to market layout, and are more willing to make emotional choices. On the one hand, this has created NIO’s unique humanistic temperament, but on the other hand, it has also caused the current chaos.

(2) The LeTV model is unsustainable. Is power exchange really the future?

Last year, NIO’s financial situation was already very bad. In 2022, NIO’s net loss for the whole year was 14.4371 billion yuan, of which 5.786 billion yuan was lost in the fourth quarter alone.

What is NIO’s response? At the same time as announcing the 2022 annual report, NIO said that 1,000 replacement stations will be built in 2023, and 500kW ultra-fast charging will be deployed "incidentally".

Why does NIO do this? In fact, it is to exchange services for the market. Compared to doing battery research and development, or building a battery production line. The return on investment ratio of power exchange services is immediate, at least the power station is actually increased. Tesla’s 4680 battery has cost a lot of money, and it has not been mass-produced for three years. If such investment is replaced by a power station, at least there is a real physical site. This is considered a major highlight of NIO. After all, for many users, power exchange is indeed very practical.

At the same time, NIO is "immune" to all price wars. No matter how Tesla and BYD are involved, NIO always insists on not reducing prices, which safeguards the interests of regular customers to the greatest extent.

But the crux of the problem is that today’s tram technology is becoming more and more mature, and the battery life is also constantly improving. When the actual battery life of high-end trams exceeds 500km, the added value brought by power replacement has become lower and lower.

At this time, consumers may pay more attention to the benefits. After all, the B-class ET5 sells more than 300,000, and the C-class Feifan F7 only sells 210,000, and the service seems to be less important.

In order to promote power exchange, NIO adopts the typical "LeTV model". The power exchange business is independent and placed outside the listed company, and then the power exchange business is continuously subsidized through the listed money. This seems "seamless", but as the NIO customer base continues to expand, the resources occupied by power exchange are also increasing, which will eventually feed back to the car price, that is, the price of NIO cannot be lowered.

That is to say, regardless of whether the battery is replaced or not, NIO’s users will eventually have to pay for this business. This is not a problem when sales increase, because doubled users can share these costs equally. But when NIO’s sales do not rise but fall, how can new car owners support the existing huge car owner base?

(3) To have faith, we must also look at the product

In the past few years, NIO could be said to be buying cars and giving away "Moments". There were NIO owners around Kung Fu Cars, and they were truly proud of their cars. They were very proud of NIO’s various activities and praised NIO’s various services.

But NIO should also realize that while this segment of consumers is important, they are far from the whole market. Most ordinary users still want high-quality and affordable models.

Not long ago, NIO launched the power station swap wish list function on the NIO App, where consumers participate in recommending the location of the power station. This may seem like a very "democratic" approach, but it may not be a good choice for the market. The location of the power station should be like opening a store, and "professional" choices should be made according to the local flow of people and the layout of the supplementary facilities, so as to ensure the interests of more car owners, not just the car owners to "vote".

The layout of products and technologies must be based on "professionalism", not emotion. Just like talking to the ideal engineer before about why the ideal doesn’t make cars, he replied that because the ideal customers at this stage are mainly family users, and the space of cars is difficult to meet, so he does not consider highlighting car products for the time being; when talking to the JK technicians about product definition, they said that it is not easy to break the game as a latecomer, and finally chose a relatively niche and the demand is not small.

To put it bluntly, if the market is already very crowded, as a latecomer to enter, there is a high probability that it will be cannon fodder. If there are still some gaps in the market, companies have a chance, provided that the price and positioning are appropriate in all aspects.

In a situation where all opponents are highly nervous, NIO’s careless market play, although it does seem to be a light weight, is inevitably gradually thrown away.

(4) Kung Fu shooting

In 2019, NIO was on the verge of bankruptcy because it could not raise money, and later Hefei City’s investment of 7 billion yuan saved it. I never thought that in this short two or three years, NIO would have to put himself in the "ICU" again, which has to be sighed.

Not long ago, Li Bin came out to reassure investors, saying that NIO was currently urgently saving itself, focusing on the four major fields of chips, mobile phones, sub-brands, and batteries. I don’t know if investors heard it or not. At least in Li Bin’s opinion, NIO’s product and technology layout is fine, so what kind of changes can be expected to be made.

Combined with the dilemma of Weimar, perhaps the entrepreneurial path of the first generation of new forces is about to be turned over.

Beijing urban management changes new uniforms, and each player has a number on his chest.

  Since yesterday (October 1st), the city’s urban management team members in Beijing have started to carry out law enforcement inspections with new uniforms. Recently, the Municipal Urban Management Law Enforcement Bureau has uniformly renewed the uniforms and signs of law enforcement personnel in the city’s urban management system. On the first day of the Eleventh Golden Week, the city’s environmental order was good. During the festival, all urban management and law enforcement departments will take a break and take up their posts, focusing on strengthening the prevention and control of bustling commercial districts and characteristic blocks, major transportation hubs, large-scale gatherings, activities and other crowded areas.

  After asking the way, the tourist said, Have you changed your uniforms?

  "Have you changed your uniforms?" Yesterday morning, outside the East Palace of the Summer Palace, Mr. Li, who was traveling from Hebei to Beijing, was surprised after asking the urban management team for directions. He said: "I mainly asked the city management for directions in the Bird’s Nest two days ago, and the answer was very detailed. I still have an impression of the previous uniforms."

  Beijing Youth Daily reporters saw in Qianmen and the Summer Palace and other popular National Day attractions that all urban management team members have put on new uniforms and started to perform their duties. The clothing color is navy blue, with a golden logo, and each team member’s number is on the chest.

  According to reports, the new uniforms mainly consider adapting to the fact that urban management law enforcement workplaces are mostly outdoors and on the streets, which is convenient for duty activities. This is also the requirement of the Municipal Urban Management Law Enforcement Bureau to implement the "Administrative Measures for the Supply of Clothing and Signs for Urban Management Law Enforcement" by the Ministry of Housing and Urban-Rural Development, strengthen the construction of urban management law enforcement teams, and further promote standardized and civilized law enforcement.

  Solve the problem of people who are not empty in the three-meal car

  After the flag-raising ceremony yesterday morning, crowds poured into Qianmen area, and the law enforcement team members of Dongcheng Urban Management began to guide the crowd. According to reports, in view of the relatively dense number of tourists watching the flag-raising during the holiday season, Dongcheng City Management has sent six law enforcement teams to strengthen the deployment in Qianmen Arrow Tower, Qianmen East Street and Chang’ an Avenue from 5: 00 every day, and sell tourist goods to the following tourists. Personnel engaged in unlicensed catering will be disposed of promptly and quickly.

  在东城,每天将有300余名队员巡查在全区各个街道和社区,发现各类问题及时解决。在簋街、南锣鼓巷及北京站等重点地区,更是每天32个车组全天连续14小时定人定岗盯守,队员一日三餐均在执法车内解决,确保每个时段岗位不空人。

  节日期间 北京城管全员停休

  为确保今年国庆期间环境秩序良好,节日期间城管执法部门全员停休,全员上岗,实名管控,重点对无照经营、非法运营、非法小广告、占道经营、店外经营、非法停车场等环境秩序问题进行查处,全面遏制重点地区环境秩序类问题。

  黄金周期间,城管执法部门重点加大对天安门及周边地区、长安街沿线,故宫、奥林匹克公园、什刹海、恭王府、八达岭、十三陵及市属11大公园,繁华商业区和特色街区,主要交通枢纽,大型集会、活动等人流密集地区的防控力度。同时对违规户外广告、牌匾标识、夜景照明、山寨指路牌、临窗广告以及车身广告等,及时督促责任人进行拆除、清理、维修或更换,对附带电话号码的,及时进行警示提醒。

  According to the person in charge of the Municipal Urban Management Law Enforcement Bureau, the management of construction sites will continue to be strengthened during the festival, and the construction enclosures in key areas will be checked according to the specifications, and the construction dust will be strictly controlled, and the management of construction waste transportation will continue to be strengthened to prevent road spillage; Increase the control of illegal activities such as open-air barbecue, burning garbage and white pollution. Visit and investigate the gas supply, users, kitchen waste generation and collection and transportation units around the key security areas one by one, and rectify the problems.

  Urban management volunteers help serve tourists.

  In addition, the urban management law enforcement department, in conjunction with the Beijing Urban Management Volunteers Association, set up urban management law enforcement publicity service stations in tourist attractions and window areas during the National Day to provide tourists with services such as inquiries, directions and simple medical care while monitoring the environmental order.

  Yesterday, in Qianmen Street, Nanluoguxiang Pedestrian Street, Summer Palace and other areas, volunteers organized by urban management departments participated in the publicity of laws and regulations, stopped uncivilized behavior, and provided some services urgently needed by tourists, such as directions.

  The person in charge of the Municipal Urban Management and Law Enforcement Bureau said that mobilizing members of the association, volunteer groups and the general public to actively participate in the maintenance of the holiday environmental order, especially guiding social units in key areas to actively participate in environmental governance and rectification, can jointly create a beautiful and clean urban environment.

  Text/Reporter Li Tao

  Photography/Reporter Wang Zhenlong Cui Jun