China’s first "cell knife" surgery for 20 years: the "brave" dance on the tip of the knife

  He pioneered functional neurosurgery in China and was the "first person in cell knife" in China … … In the field of functional neurosurgery in China, Li Yongjie is a "myth". Under the dazzling aura, in essence, he will always be a scientist doctor who constantly explores new fields and a doctor who stands in the way of death and disease.

  Li Yongjie is a 79-grade college student — — After the reform and opening up, the first batch of college students changed their fate through the college entrance examination. In the early 1990s, with the tide of studying abroad, he learned "one-handed" skills in traveling to the west. Although he got the green card, he resolutely gave up the choice of returning to China. In just 20 years, he created and led a discipline to rank among the international "first phalanx" … …

  At the time of 40 years of reform and opening up, the 1.5 million-word book Functional Neurosurgery edited by Li Yongjie was published. A book, a person; A discipline, an era … …

  Open Functional Neurosurgery, walk into xuanwu hospital Institute of Functional Neurosurgery and Beijing Institute of Functional Neurosurgery of Capital Medical University, approach Li Yongjie’s team, and learn about the development of functional neurosurgery, as if seeing the dance of "brave" on the tip of a knife, and the wonderful dance skills are the never-ending steps … …

▲ Family photo of 2018 Beijing Institute of Functional Neurosurgery. Photo courtesy of respondents

▲ Family photo of 2018 Beijing Institute of Functional Neurosurgery. Photo courtesy of respondents

  Xinhua Daily Telegraph Press Conference Morality

  At the fork of Zheng Xinyi’s fate, Li Yongjie, his attending doctor and director of Beijing Institute of Functional Neurosurgery, stood there with a smile — — It was he and his team who realized the dream that "China Forrest Gump" had broken one place through surgery.

  July 12th is the 20th anniversary of the first "cell knife" operation in China. Xinhua Daily Telegraph reporter entered the organization that has become the largest number of brain pacemakers implanted in the world for 10 consecutive years — — Xuanwu hospital Institute of Functional Neurosurgery and Beijing Institute of Functional Neurosurgery of Capital Medical University.

  He was admitted to Peking University in 1979, studied abroad in 1994, and returned to China 20 years ago to establish the Beijing Institute of Functional Neurosurgery. A few years ago, he began to explore the society to run doctors and set up outpatient departments to help more people see and be optimistic about the disease … … In the recent 40 years, Li Yongjie’s fate has been closely linked with the changes of a discipline and an era.

▲ Professor Li Yongjie.

▲ Professor Li Yongjie.

  Open your eyes and see the world:

  From "the first person in cell knife" to "a seed"

  The human brain is one of the most amazing and complicated substances in the world. To move a "knife" on the brain requires not only courage, but also "real kung fu".

  The operation that Li Yongjie cured Zheng Xinyi was called "Deep Brain Stimulation Operation". Simply put, it is to put electrodes deep in the human brain. The scientific principle is that the dyskinesia of human body is caused by pathological changes in some brain cells, and their symptoms can be controlled and regulated by electrical stimulation of the pathological cells.

▲ Professor Li Yongjie performs stereotactic surgery for patients.

▲ Professor Li Yongjie performs stereotactic surgery for patients.

  Such an operation sounds simple, but in fact, human beings didn’t realize the relationship between human brain and consciousness and behavior until the end of the 19th century. The accurate treatment of brain tissue by surgery can be traced back to the emergence of stereotactic technology in 1947 — — At that time, the disease targeted by this technology was Parkinson’s disease, which was called "immortal cancer".

  At first, the patient’s hands and feet showed rhythmic tremor, slow movement, difficulty in tying shoelaces and buttons, and difficulty in putting on and taking off shoes and socks. After 5 to 15 years of illness, he gradually lost his mobility … … Parkinson’s disease is a slowly progressive disease, which mainly occurs in middle-aged and elderly people. Muhammad Ali and mathematician Chen Jingrun all suffered from this disease.

  In 1994, Li Yongjie, who had just gone abroad for postdoctoral studies, first came into contact with the cutting-edge microelectrode-guided stereotactic neurosurgery. This is a technique to stop the patient’s body tremor by destroying the "tremor cells" in the brain, which is vividly called "cell knife".

  As a neuromodulation surgery, it uses stereotactic method to locate accurately, implants stimulation electrodes in the human brain, and controls the stimulation parameters of the electrodes in the brain through the remote control device in vitro, so as to control and improve the patient’s disease symptoms. It is the most successful case for human beings to realize the dream of "brain-computer dialogue".

  "This kind of deep brain stimulator, also known as brain pacemaker, is the most advanced technical means for the treatment of functional encephalopathy in the international medical community since the beginning of the 21 ST century, among which the treatment of Parkinson’s disease patients is the most mature and common." Today, Li Yongjie still remembers the shock of that moment.

  After the patient who was treated in the operating room was accurately located in the skull, a very thin electrode went deep into her brain to find the abnormal cells, and then it was "destroyed" by radio frequency heating. Within a few seconds, the violent tremor of the patient’s right hand disappeared, and her tears welled up in her eyes: "Oh, my God, it’s stopped for 10 years … …”

▲ The Institute was established in 1998-Dr. RP-Iacono, a famous functional neurosurgeon from the United States, came to congratulate him personally.

▲ The Institute was established in 1998-Dr. RP-Iacono, a famous functional neurosurgeon from the United States, came to congratulate him personally.

  "The whole world seems to be silent, and I can only hear the voice in my heart: I must master this technology!" Li Yongjie, 57, will never forget the moment when he decided his future academic direction and even his life destiny.

  At that time, this advanced surgical technique was still a blank in China, and doctors also called Parkinson’s disease "tremor paralysis". Li Yongjie, who has been a doctor of medicine in China for several years, knows very well that there are tens of millions of patients with nervous system functional diseases like Parkinson’s disease in China, and high-level brain surgery intervention is urgently needed.

  After graduating as a postdoctoral fellow, Li Yongjie did not hesitate to join the world-renowned stereotactic neurosurgery — — The medical center of Linda University in Rome has mastered all the techniques of "cell knife" in only two years.

  "There are so many patients in China, I want to go back to China and bring back the technology I have learned!" Li Yongjie’s inner voice rang again. Comfortable life, clean environment, American green card … … Nothing can stop him from returning to China.

  "I left without hesitation." Li Yongjie said firmly.

▲ On July 12th, 1998, Li Yongjie completed the first stereotactic cell knife operation in Beijing Institute of Functional Neurosurgery.

▲ On July 12th, 1998, Li Yongjie completed the first stereotactic cell knife operation in Beijing Institute of Functional Neurosurgery.

  On July 12th, 1998, the first "cell knife" operation in China began in xuanwu hospital. Li Yongjie, who returned from school, is a surgeon, anesthesiologist, radiologist and nurse … … Because no one knows how this "sophisticated" operation is done, he needs to personally control every link.

  Heading, taking the patient to the nuclear magnetic room for brain scanning, positioning the surgical target, calculating the target position, craniotomy, drilling, inserting a very fine puncture needle to reach the target position, and inserting a microelectrode &hellip along the needle track; … Unconsciously, eight hours passed, and Li Yongjie, who was immersed in it, didn’t feel it at all. The doctors and nurses on the sidelines saw that the error of electrode positioning was less than 1 mm, and the patient’s trembling hand gradually stopped during the operation.

  "The human brain is a black box. Stereotactic technology is a bit like GPS and must be accurate to the millimeter." Li Yongjie said.

  Functional Neurosurgery Newsletter is a peer-to-peer exchange publication run by the Institute. The cover of the 10th issue published in April 2012 is a picture of Swiss national hero william tell aiming at an apple on his son’s head not far away under the oppression of colonists.

  "Through the distant time and space, we are capturing William’s breath in the picture, pulse diagnosis’s pulse, and appreciate each other’s heart is sympathetic." Li Yongjie wrote in the article "Courage and Responsibility Create Glory" on the front page of the magazine, "Because our profession is a doctor who saves lives, and the disease is ‘ Magic ’ The doctor is a bow and arrow maker. Facing the eyes of patients seeking help or even despair, facing the challenges of difficult and complicated diseases, and facing the medical risks and sociological risks brought by treatment, we are tested and challenged every day. This not only requires our confidence in our own knowledge and skills, but also challenges our courage and responsibility. "

  Neurosurgery, especially stereotactic surgery, is like shooting an apple with a bow.

  "This requires a high degree of accuracy, and no mistakes are allowed, so as to ensure that patients are safe, and ‘ Shoot ’ The disease is invisible. " Li Yongjie said.

  "It feels amazing." Lu Xiaoli, a doctor who witnessed the whole operation, remembers that after the success of the operation, more and more patients came here. By the end of 1998, Li Yongjie’s team had been able to perform dozens of "cell knife" operations every month, and a set of scientific operation standard procedures were established, and the operation time was shortened to an average of two hours.

  "I am just a seed, bringing this technology back to China and blossoming everywhere." Li Yongjie, who is known as the "first person of cell knife", said modestly that if he has made any contribution, it is to make the stereotactic technology develop more finely and safely in China.

▲ In 1999, the National Parkinson Foundation awarded Beijing Institute of Functional Neurosurgery the title of "Clinical Center of Excellence".

▲ In 1999, the National Parkinson Foundation awarded Beijing Institute of Functional Neurosurgery the title of "Clinical Center of Excellence".

  Parkinson’s disease is the most common type of dyskinesia. Epidemiological statistics show that there are 2 million patients in China, accounting for 40% of the total number of patients in the world. Due to the aging of the population, the incidence of Parkinson’s disease is still increasing, and it has become one of the common diseases in the nervous system of middle-aged and elderly people.

  In 1817, the British doctor Parkinson confirmed Parkinson’s disease in his book "On Tremor Paralysis", and then the international medical community named the disease after him.

  "This year is 201 years since Parkinson’s disease was confirmed." Li Yongjie said, "Before I went abroad, the name Parkinson’s disease had been used abroad for more than 100 years, and this disease was still called ‘ Tremor paralysis ’ . Now the country is also called Parkinson’s disease, which is the result of everyone opening their eyes to see the world. "

  The pioneering and exploration of Beijing Institute of Functional Neurosurgery has made countless patients see hope.

  As of July 12, 2018, in the past 20 years, Beijing Institute of Functional Neurosurgery has performed stereotactic surgery for 6,690 patients with dyskinesia, involving 13 types of functional neurosurgical diseases: Parkinson’s disease accounts for more than 3/4, followed by primary tremor (10.87%) and dystonia (7.17%), and other dyskinesia only accounts for 5.74%— — Include cerebral palsy, TIC disorder, Parkinson’s superposition syndrome, voluntary movement’s disease, chorea, etc.

  "At the beginning of returning to China for three or five years, we were fighting alone. In the last five or six years, hospitals and universities everywhere can’t wait to develop functional neurosurgery. " Li Yongjie said.

▲2009-9-18- Professor Ali-Rezai, an American expert on dyskinesia, visited and Professor Li Yongjie signed a book.

▲2009-9-18- Professor Ali-Rezai, an American expert on dyskinesia, visited and Professor Li Yongjie signed a book.

  The brave are invincible:

  Let functional neurosurgery blossom in China in 20 years.

  Starting from the first "cell knife" operation 20 years ago, China has established a multi-level and all-round discipline framework of functional neurosurgery, which focuses on dyskinesia, epilepsy surgery and pain, and spreads to neuromuscular spasm and psychosurgery.

  Li Yongjie’s "battlefield for one person" has also become a "team competition".

  At that time, xuanwu hospital established the Beijing Institute of Functional Neurosurgery because of his return, which is the first clinical treatment and scientific research institution in the field of functional neurosurgery in China. Since 2009, it has become the world’s largest "Deep Brain Stimulation Treatment Center", and the number of brain pacemakers implanted has been the first in the world for 10 consecutive years.

  "This is the result of a team competition, but the high technology of the brain stimulator comes from the other side of the ocean. No matter how big the implant is, it just follows, not leads." Li Yongjie is very sober. "It’s my real mission to return to China to start a business, not to be a flash in the pan, but to develop steadily."

  Faced with the huge medical demand and the blank field of functional neurosurgery in China at that time, the doctor with elegant appearance and slow speech showed the well-known word "courage" and shouldered the two burdens of talent training and discipline construction.

  It is hard to imagine that when Li Yongjie cured Zheng Xinyi’s "spastic cerebral palsy" in 2010, brain electrode implantation was still in the early clinical exploration in the world. This means that his frontier exploration will inevitably have the risk of failure.

  Li Yongjie admits that although he "cherishes feathers", he wants to be a good brain surgeon, "focusing on intelligence in the short term, ability in the medium term and responsibility in the long term". To this end, he set a rule for surgery: "I will do the most difficult, latest and risky surgery!"

▲ Professor Li Yongjie performs endoscopic surgery.

▲ Professor Li Yongjie performs endoscopic surgery.

  Once, Li Yongjie met an epileptic with a particularly complicated condition. After she failed in an operation in a foreign country, she was introduced to see a doctor by a medical elder. But after an impeccable craniotomy, her condition actually relapsed. This means that the previous judgment of the lesion is likely to be wrong.

  When Li Yongjie was called to the ward by his colleagues, what he saw was such a scene: the patient’s mother was sitting on the windowsill, desperate. Based on careful observation, Li Yongjie made a decisive second craniotomy and confirmed that the real lesion was in the parietal lobe of the brain, less than 2 cm away from the motor cortex of the brain.

  Do you want to do the third craniotomy? Who will do it? Li Yongjie did not hesitate to stand before the operating table. He carefully removed the focus cells as big as the fingernail, avoiding the dangerous motor cortex injury.

  "The patient is only 16 years old. If he is paralyzed by surgery, the young doctor may not be able to bear this huge psychological burden, then I will come." He smiled and recalled as if those thrilling "moments of life and death" were as usual.

  Dr. Lu Xiaoli, who has been following him, commented that he was "not angry and arrogant" — — "When he is around, everyone relies on him from the heart, which is the personality charm of Professor Li".

  He is honest with others.

  "If you don’t look at it, as long as I pick it up, I must be responsible for the patient to the end." Li Yongjie said, "It must be that those who dare to take responsibility make rapid progress, and those who are afraid of accidents make slow progress. In the end, it is better than taking responsibility."

  "Teacher Li often tells us that being a good doctor is the first priority. For diseases that can be cured, the treatment should be serious and accurate, and the best treatment plan should be discussed for difficult cases. For diseases that have no treatment for the time being, patients and their families should correctly understand and face the disease positively. ‘ Sometimes it’s healing, often it’s helping, always comforting ’ 。” Zhou Changshuai, a student in Li Yongjie, once quoted this sentence to describe his mentor in an article entitled "The Short Story of big doctor".

  More than 100,000 patients from all over the world were diagnosed and treated, and more than 10,000 cases were treated by surgery … … After 20 years, Li Yongjie has realized his ambition of returning to China: 16 "Xuanwu workshops" for hospitals across the country have trained a high-level "national team" of functional neurosurgery and trained thousands of doctors across the country; Cutting-edge technologies such as "cell knife", deep brain stimulation and endoscopic surgery have been introduced into China, and the number of diseases that can be diagnosed and treated has expanded to more than 30.

  "I am obsessive-compulsive disorder and perfectionist." Li Yongjie said, "Scientific research is a kind of spirit, attitude and method. To treat scientific research as work and work as scientific research, we must understand and clarify, run the spirit of scientific research through our work, and constantly expand the scope of application of technology."

  Someone asked Li Yongjie, "Aren’t you afraid to teach your disciples and starve your master?" He laughed: "I have so many new technologies and fields to learn, how can I have time to think about them?"

▲ Professor Li Yongjie is doing popular science propaganda in the column "The Road to Health".

▲ Professor Li Yongjie is doing popular science propaganda in the column "The Road to Health".

  Parkinson’s disease, primary disorder, dystonia, TIC disorder, voluntary movement’s disease, cerebral palsy, myotonia and other motor disorders, various epilepsy diseases, chronic pain such as central pain, peripheral nerve injury pain, cancer pain, visceral pain, soft tissue pain, low back pain, neck and shoulder pain, and neurospinal diseases such as lumbar disc herniation and cervical disc herniation & HELIP; … Experts from Beijing Institute of Functional Neurosurgery have treated or operated on more than 30 diseases recorded in Functional Neurosurgery.

  "In the field of functional neurosurgery, a comprehensive platform for treating diseases like ours can’t be found all over the world." Li Yongjie’s tone is gentle, but he is confident and proud. "In 20 years, I set up a platform for discipline development and brought out a team. Even if I retire, this subject will continue to develop. "

  In the conference room of the Institute of Functional Neurology, picture frames are hung on the wall in order, and each one is longer than the other — — Because this is the annual photo of the Institute.

  "Under the leadership of Director Li, our group photo lasted for 20 years. We are a big family and the team is getting bigger and bigger, so the group photos are getting longer and longer. " Lu Xiaoli said.

  Looking back on the 40 years of reform and opening-up, Li Yongjie was filled with emotion: "We have caught up with the era of reform and opening-up, which is the best and fastest period of economic, social, knowledge, science and technology development in China for thousands of years. From an ignorant teenager to a medical expert and academic leader, from an entrepreneur with dreams to the ideal landing and rooting, my growth and harvest are all thanks to the times. "

  "From an idiotic dream to a dream come true, I am more like the child running on the beautiful beach. Among the sea goods surrounded by waves on the beach, I am delighted to find several colorful shells … … Looking around, there are so many such children! "

  Ten years ago, Li Yongjie wrote this passage with emotion, which is meaningful today.

▲ In 2015, Professor Li Yongjie won the title of "Top Ten Health Guards in the Capital".

▲ In 2015, Professor Li Yongjie won the title of "Top Ten Health Guards in the Capital".

  Always on the road:

  A restless scientist

  Sharpen a sword in 20 years.

  The team of more than 100 people led by Li Yongjie has become the world-famous "China Team" in the field of functional neurosurgery, and ranks among the international "first phalanx" — — Beijing Institute of Functional Neurosurgery was awarded the title of "Clinical Center of Excellence" by international institutions as early as 1999, becoming the only clinical institution in Asia to receive this honor.

  What else does he want?

  "I am a restless person, and I naturally like to do something new and different." There was a childlike look on his face. "I hope to be recognized as a scientist doctor."

  In fact, it was Li Yongjie’s childhood dream to be a scientist, but it was accidental to study medicine.

  In 1960s, he was born in an ordinary family in Datong City, Shanxi Province. In that special time when "sports followed sports", Li Yongjie was a "silent, timid" child because of his family background of "rich peasants", and he was "aged and lonely out of proportion to his age".

  But under his seemingly "juvenile maturity" appearance, there is an interesting and curious soul hidden. He loved natural science since he was a child, and when he was 6 years old, he had a whim to make a perpetual motion machine with water currents and waterwheels. After the Tangshan earthquake, he hung a small hammer with enameled wire and passed through the ring. As long as it shook, it would trigger the ringing of the electric bell. He was very proud of this homemade "seismograph". At the age of 15, he climbed onto the roof to install an antenna, and the self-made "crystal receiver" actually received china national radio’s voice … …

  In 1977, China resumed the national college entrance examination and entered the "scientific spring" with emphasis on education and knowledge.

  "The resumption of the college entrance examination has restored the vitality of the social class." In 1979, Li Yongjie, who won the first prize in Shanxi Physics Competition, gave up the opportunity to attend the university of Shanxi Province without taking the exam and chose to take the college entrance examination, and was admitted to the top 20 in the province. His mother said, "If only our family could have a doctor, you could study medicine", which made him filial and medicine accompany him ever since.

  In 1991, Li Yongjie, who received a doctor’s degree in medicine from Shanxi Medical University and published two English papers in Brain Research magazine, saw the huge gap between domestic and foreign advanced technology. A strong thirst for knowledge made him "desperate" and sold his newly allocated house to study abroad.

  "My growth and harvest are all thanks to the times. If I don’t catch up with the golden age of 40 years of reform and opening up, I may not be able to dominate my own destiny." He said, "Therefore, I firmly believe that my seed will be the home only if it falls on the land of the motherland, and it will grow most vigorously."

  "The door of opportunity opened by reform is getting bigger and bigger, and the chances that individuals can dominate their own destiny are getting higher and higher." Li Yongjie, which chose to return to China, has indeed achieved "the most vigorous growth" — — Under his leadership, Beijing Institute of Functional Neurosurgery keeps track of the latest development of functional encephalopathy in the world, improves technical methods, improves the level of treatment and expands the scope of treatment.

▲ In 1999, Professor Li Yongjie communicated with the Swedish doctor LV-Laitinen, a pioneer of functional neurosurgery.

▲ In 1999, Professor Li Yongjie communicated with the Swedish doctor LV-Laitinen, a pioneer of functional neurosurgery.

  In March 1999, the Institute of Functional Neurosurgery successfully treated Parkinson’s disease with subthalamic nucleus destruction technology, and in the same year, deep brain stimulation technology (brain pacemaker therapy) was developed to treat Parkinson’s disease.

  In May, 1999, the first operation to treat generalized torsion spasm was successful.

  In the second half of 1999, the first operation to treat spastic torticollis, chorea and Tourette’s syndrome was successful one after another.

  In the new century, after creatively expanding the scope of surgical treatment to other dyskinesia diseases, his team began to pay attention to the work in the field of surgical treatment of epilepsy and pain … …

  "Yongjie’s team has always led the development of functional neurosurgery in China, from treating Parkinson’s disease to epilepsy to pain … …” Professor Yuxi Liu of Shanxi Medical University said.

  In the past three years, the average annual operation volume of Beijing Institute of Functional Surgery was over 1,600, and a team with their own strengths and vitality also grew up — —

  Zhang Guojun and Yu Tao focus on the localization of epileptogenic focus and microsurgical treatment of intractable epilepsy; Hu Yongsheng specializes in surgical treatment and nerve regulation of chronic pain; Zhu Hongwei is good at neurospinal and cranial neuropathy; Li Jianyu has 20 years of experience in surgical treatment of dyskinesia … …

▲ Professor Li Yongjie gave a keynote speech at the 2017 Chinese Conference on Functional Neurosurgery.

▲ Professor Li Yongjie gave a keynote speech at the 2017 Chinese Conference on Functional Neurosurgery.

  In September 2017, the Huaxia Conference on Functional Neurosurgery was held in Beijing, and more than 20 top scholars in the world and more than 100 well-known experts in China arrived as scheduled.

  In his speech at the conference, Li Yongjie introduced the summary of the world’s largest surgical cases of dyskinesia completed by the Institute in the past 20 years: a total of 6,467 cases were treated by surgery, and it was also found that the risk of Parkinson’s disease in men was 1.46 times that of women, and the overall dyskinesia was 1.45 times; At the age of onset, half of the patients with Parkinson’s disease developed before the age of 53, and half of them received surgery before the age of 61.

  In the first 10 years after returning to China, Li Yongjie devoted himself to improving the diagnosis and treatment of Parkinson’s disease and epilepsy to the international level, and then he turned his attention to the treatment of chronic pain.

  "The most common and harmful pain is disc herniation. My focus now is how to make it more meticulous and minimally invasive, in line with international concepts and models." He said.

  Exploration is always on the road — —

  "Science, solve ‘ Day ’ The problem; Technology, solve ‘ Land ’ The problem. I am still optimistic about the prospect of surgical treatment of emotional disorders such as major depression, hoping to find that key and open the door to the connection between heaven and earth. " He said.

▲ Professor Li Yongjie spoke at the 10th anniversary celebration of Beijing Institute of Functional Neurosurgery.

▲ Professor Li Yongjie spoke at the 10th anniversary celebration of Beijing Institute of Functional Neurosurgery.

  Li Yongjie, a member of the Standing Committee of the Beijing Municipal Political Consultative Conference, has repeatedly encouraged and called for the reform of the medical system. He has also done his best: in 2014, he promoted social capital to set up the Beijing Xidian Clinic, so that the advanced national specialized medical model can take root and explore a new path of graded diagnosis and treatment.

  "Medical reform has entered the deep water area, which requires not only the skills of those who bow and arrow ‘ Emboldened ’ It requires the sense of responsibility of those involved in medical reform and the courage and responsibility of reformers. The reform of the medical system is risky, and it is even more risky if the medical system is not reformed. Go on the road with responsibility, courage and responsibility, because we believe that after twists and turns and even dangers, we will eventually reap glory. " Li Yongjie’s words spoke out the common aspiration of the participants in the western clinic.

  "Every discipline has its scientific, systematic and complete requirements and development expectations … … As far as I am concerned, more than 20 years of study, research, practice and teaching experience in the field of functional neurosurgery are even more eager for it. " In 2018, Li Yongjie led the team to compile the lifelong learning and practice into a 1.5-million-word masterpiece Functional Neurosurgery. "The editorial team adheres to the concept of combining theoretical interpretation with clinical practice, and hopes to weave a whole picture in the field of functional neurosurgery with this context, hoping that it will become a classic in the field of functional neurosurgery."

  "Patients with functional diseases of the nervous system account for more than 10% of the total population, and there are tens of millions of people who need interventional therapy. The number of people who can benefit from surgery is conservatively estimated to be as high as 5 million, which is about 10 times that of patients with brain tumors. Such a huge demand for medical services cannot be ignored, and historic opportunities for discipline development should not be missed. " He appealed in the preface.

  In October 2017, Zhu Hongwei and Zhang Jiaxing of Beijing Institute of Functional Neurosurgery participated in an important international academic conference in neurosurgery, and found that this conference "no matter the lecture content or the frontier field display, the function and nerve spine account for nearly half, and everyone is working hard on stereotactic, navigation and artificial intelligence … …”

  "This conference really shows the future development direction of neurosurgery, from which we can see our shortcomings and our status. It is proud that many of the work of the Beijing Institute of Functional Neurosurgery is at the forefront of the world. I believe that in new fields, we will also keep up with the international pace and make our own characteristics in the field of neurospinal surgery. " Zhang Jiaxing said.

▲ Playing basketball is Li Yongjie's favorite sport.

▲ Playing basketball is Li Yongjie’s favorite sport.

  In the face of achievements, Li Yongjie was unusually sober.

  "We let the international advanced technology take root and bear fruit in China, and even ran away with international counterparts in clinic. Of course, there is innovation in this, but deep brain stimulation technology was invented abroad, and we still lack real original inventions. We need to open up new fields and invent new equipment, and start with creativity, research and development, market development and resource integration to establish a complete chain of scientific research and industrial development. " Li Yongjie said, "From quantitative change to qualitative change, this possibility has greatly increased now."

  Li Yongjie revealed that his team is brewing non-invasive surgery. "This is the next step in surgery and treatment, and it will be a big breakthrough. I am optimistic about it."

  On the occasion of Functional Neurosurgery in Fu Zi, it was the time when Alpha Go defeated the top human Weiqi players.

  "The brain has 60 billion to 70 billion brain cells. If you regard them as planets, then the brain is as infinite as the universe." Li Yongjie, who is optimistic about brain-computer interface, said excitedly that if we can join hands with engineers, it may connect human imagination and mobility. "That will open up a new world of functional neurosurgery".

Many old acquaintances returned to Morena Bacalin to join Dead Waiter 3.

Deadpool

Deadpool

     On April 27th, Beijing time, according to foreign media reports, Morena Bacalin and Stefan Kapicic returned to Dead Waiter 3 and continued to play Vanessa and Guinness.

  Karan Soni and leslie uggams, old acquaintances who had previously announced their return, continued to play the roles of taxi driver Dobinder and roommate blind wife Al.

  This film is the first film in which "Deadpool" joins MCU, with ryan reynolds returning to the leading role, Hugh Jackman "Wolverine" newly joining, and Emma Colin and matthew macfadyen also starring. Directed by shawn levy, it will be R-rated, and it is planned to start shooting in May this year and be released in North America on November 8 next year.

  Deadpool, whose real name is wade winston wilson, is a fictional character created by Marvel Comics. He first appeared in New Mutant # 98 (published in February 1991). At first, Deadpool was set as a super villain, but after he was transferred from New Mutant to Agent X series, he gradually became an anti-hero who attracted more attention from readers. Deadpool is a mercenary and assassin who has been disfigured and thus deeply troubled. He has strong self-healing ability and superhuman physical quality. Because of his joking style, especially his tendency to break the fourth wall to create humor or play gimmicks, he won the nickname "mouth gun mercenary"

  Deadpool’s popularity is also reflected in his appearance in other media. In the comic book series Cable and Deadpool in 2004, Deadpool called his scar "the intersection of ryan reynolds and Sha Pigou". Reynolds finally played Deadpool in the X-Men Movie Series, and appeared in Wolverine (2009), Deadpool (2016) and its sequel Dead Servant 2 (2018). On March 20, 2019, Walt Disney Company returned through the merger of 20th Century Fox, X-Men and Fantastic Four. But only Deadpool confirmed that he would not restart or re-cast, and Deadpool, played by Ryan Reynolds, would return and join the Marvel movie universe.

  Wade winston wilson lost his father when he was young, and his mother became desperate. Later, he also left home to find another way. However, there are two mothers and three fathers in his memory, but no matter which version, they all died in the end. Later, his friends, Ply Si Tong and Scott, agents of S.H.I.E.L.E.L.D., discovered in an incident that he was controlled by a villain named Butler in his youth and then killed his family, but Deadpool himself didn’t know at present.

  When he grew up, Wade joined the Canadian Special Operations Forces Command and became a mercenary. He was sent to kill a man named Wade T Wilson in a mission, which reminded Wade of his real name.

  As one of the most violent characters in the X-Men, Deadpool accepted the experiment of "X-Weapon" in the early stage to treat cancer, and implanted the regenerative healing factor from Jingang Wolf into his own body. Even after being tortured, he was able to regenerate quickly, and his body was torn apart and restored to its original state, which led to the excessive growth of brain cells and became crazy. Regenerative ability and cancer cells repel each other, resulting in a body full of scars. I was deeply ashamed and didn’t want to implicate my girlfriend’s happy life, so I left her. Later, in a secret war, I met a black symbiont who just came to earth and was possessed by it. This symbiont is the venom that later possessed Spider-Man: the deadly guardian.

  Later, he found an apartment by himself, and advertised that he could accept anyone’s entrustment to kill people. Because of this, the punisher became sworn enemies with him, and even Spider-Man disliked his style very much.

  In fact, Deadpool was very kind, and after leaving the "X-weapon", he would no longer kill good people. Usually, he was hired to kill only gangsters, terrorist organizations and some famous villains in the Marvel universe. But Deadpool is very lewd. Before accepting the experiment, he originally wanted to spend the rest of his life with his former girlfriend. Later, when his girlfriend left him, he often made love everywhere.

  Deadpool is used to chatting with his other personalities at ordinary times, and has a yellow dialog box to represent his other personality, which usually makes his companions unhappy with him. Marvel Comics is one of the few people who know that they are in the comic world. In many cases, he will deliberately break the fourth wall to have a dialogue with readers. He likes to eat tacos.

  I think I have the ability to regenerate, so I can be regarded as a mutant, but because it is implanted the day after tomorrow, it is not accepted by the X-Men, so I often make trouble under an excuse, which makes the members of the X-Men have a headache.

  In private love, he has kissed and made out with many women. And once had feelings with the goddess of death, so she was cursed by Thanos, who also fell in love with the goddess of death, and became immortal, so she could not be with her. Deadpool accepted Drakula’s entrustment to bring back his fiancee, succubus queen Kela Xia (political marriage, when Drakula thought Kela Xia was his first daughter) in The Iron Hand Challenge. As a result, Kela Xia unexpectedly fell in love with Deadpool, and they got married.

  In many stories, we can know that Deadpool is a language expert. For example, in the story of Jin Gang Wolf, he translated the dialect of Wa Kanda, and in The Art of War of Deadpool, he showed that he could understand ancient Chinese, even the characters of the Warring States Period.

  It is learned from Deadpool #250 that Deadpool died in the collision between the main universe and the ultimate universe. But eight months after the secret war, Deadpool cooperated with Captain America to steal chemicals that might save his life from a sick thief.

  Later, Deadpool was recruited into The Avengers in The Extraordinary Avenger, and he used the fame brought by The Avengers to set up a bounty mercenary group (also known as the money-grabbing special attack team), but later he broke up because of poor management and Deadpool’s lack of leadership, and was later taken over by Domino.

  Thanks to the "X-weapon" experiment, Deadpool has a very strong regenerative self-healing ability and superhuman physical quality, and its regenerative ability is even stronger than that of the Wolves of Jingang. Even if his brain and heart are fatally injured, he can heal and regenerate quickly, and his body can recover quickly even if it is divided, but his regenerative ability is mutually exclusive with cancer cells in the body, resulting in scars everywhere.

  Deadpool has the ability to break the fourth wall, which enables him to talk directly with readers or audiences. This ability is also reflected in the live-action movies. He is one of the few people in Marvel Comics’s works who knows that he is in a comic world. Deadpool is also one of the most famous talkers in Marvel comics, and his talker is stronger than Spider-Man’s, so he is known as the "talker mercenary" and "the first talker in Marvel Comics". The reason behind this is actually that his mutant ability causes excessive growth of brain cells, which makes his character crazy.

  In many stories, we can know that Deadpool is a language expert. For example, in the story of Jin Gang Wolf, he once translated the dialect of Wa Kanda, and in The Art of War in Deadpool, he showed that he could understand ancient Chinese, even the characters of the Warring States period.

  Deadpool is also an expert in gun, fencing and fighting. His main weapons are pistols and two Tatsu Yamashiro. In the live-action movie, he used to turn two Tatsu Yamashiro to resist bullets fired by electric cables, and even easily killed a large group of members of the "X-Weapons" project with only twelve bullets.

  (Meng Qing)

Domestic vaccines account for more than 95% of the actual vaccination in China, and the quality is comparable to the international level.

  Vaccine is a biological product for preventing and controlling the occurrence and prevalence of infectious diseases, and it is of great significance to protect human health. The reporter learned from National Medical Products Administration that at present, China is the largest vaccine producer in the world, with 45 vaccine manufacturers, which can produce 63 kinds of vaccines and prevent 34 kinds of infectious diseases, with an annual production capacity of more than 1 billion doses. It is one of the few countries and regions in the world that can solve all planned immunization vaccines on their own.

  Taking children’s vaccines as an example, at present, China’s children’s immunization program covers 12 vaccine-preventable diseases, basically covering all key vaccine types recommended by the World Health Organization, and individual vaccines such as Japanese encephalitis are included in children’s immunization programs before other countries and regions. Since the implementation of immunization program in 1978, the R&D and production capacity of vaccine manufacturers in China has been continuously improved, and polio caused by wild strains has been eliminated, and diseases such as hepatitis B, measles, diphtheria, pertussis, tetanus, tuberculosis and Japanese encephalitis have been controlled. In particular, domestic inactivated enterovirus 71 vaccine (hand, foot and mouth disease vaccine) and recombinant hepatitis E vaccine are the first in the world.

  However, many parents still hesitate when choosing to vaccinate domestic vaccines. "There is no obvious difference between domestic and imported vaccines in terms of quality standards, safety and use." Wang Huaqing, chief expert of China CDC, said that both domestic vaccines and imported vaccines must strictly follow the requirements of the State Drug Administration, strictly carry out pre-marketing clinical research, and the production meets GMP requirements. Each batch of vaccines can only be put on the market after passing the strict batch issuance inspection. Judging from the current domestic vaccination situation, domestic vaccines account for more than 95% of the actual vaccination in the country.

  "Before the vaccine is put on the market, it is necessary to implement a strict batch issuance system, which is an important barrier in the process of vaccine delivery and circulation, that is, the drug inspection agency should inspect and review its data according to the standards, which is equivalent to adding another weight to vaccine safety besides ordinary drugs ‘ Insurance ’ 。” Wang Youchun, vice president of China Institute of Food and Drug Control, said that as early as 2006, China had managed the batch issuance of all vaccines. At present, among the more than 190 member countries of the World Health Organization, only more than 30 countries have the full supervision function of vaccines recognized by the World Health Organization.

  At the same time, in order to understand the quality status of vaccines on the market, find out quality problems and hidden dangers, and take corresponding risk control measures in time, since 2008, the national drug regulatory authorities have carried out evaluation sampling tests on some vaccines every year, that is, the vaccine products are selected from three aspects: production, circulation and use for quality inspection and result analysis. Statistics show that at present, China issues about 5000 batches and 700 million dosage units of vaccines every year. From 2006 to 2017, a total of 317 batches of unqualified vaccines were refused, with about 19 million people. Judging from the sampling inspection, the country has sampled 944 batches of vaccine products since 2008, with a qualified rate of 99.6%.

  In fact, China’s vaccine management not only follows the most stringent standards, but also the formed vaccine supervision system has passed the evaluation of the national supervision system of the World Health Organization. "This assessment is not only a comprehensive consideration of the ability of a national vaccine regulatory agency, but also the basis and premise for vaccine manufacturers in this country to apply for WHO product pre-certification and enter international procurement channels." For example, Wang Youchun said that domestic vaccines such as live attenuated Japanese encephalitis vaccine produced by Chengdu Institute of Biological Products, oral type I and type III polio vaccine produced by Beijing Beishengyan Biological Company, influenza vaccine produced by Hualan Biological Company and inactivated hepatitis A vaccine produced by Beijing Kexing Biological Company have successively passed the product pre-certification of the World Health Organization, and have been successively purchased by UNICEF and Global Alliance for Vaccine Immunization for disease prevention and control in other countries.

  With the increasingly strict supervision, in recent years, the quality standards of vaccines listed in China have reached the requirements of the World Health Organization for vaccine products, and the key indicators of some varieties are even higher than those in Europe and America. Wang Youchun said that at present, China has established a coverage vaccine "research and development — Production — Circulation — "Vaccination" has a complete vaccine supervision system, legal system and standard management, a scientific and rigorous vaccine registration and approval system has been established, and good manufacturing practice, which is in line with the international advanced level, and strict quality management standards for drug business have been implemented. (Economic Daily-China Economic Net reporter Ji Leilei)

Qiushi. com commentator: relying on labor creation to solidly promote Chinese modernization

  On the occasion of the May 1st International Labor Day, the General Secretary of the Supreme Leader extended festive congratulations and sincere condolences to the broad masses of working people throughout the country, encouraging them to vigorously carry forward the spirit of model workers, labor spirit and craftsman spirit, work honestly and diligently, be determined to innovate, dare to be the first, rely on labor creation to solidly promote Chinese modernization, and give full play to the role of the main force in the new journey of building a strong country and national rejuvenation.

  Labor is the essential activity of human beings and the fundamental force to promote the progress of human society. Marx pointed out: "any nation will perish if it stops working, not to mention a year, even a few weeks." Glorious labor and great creation are the basic viewpoints of Marxist labor view, an important interpretation of the law of human civilization and progress, and a spiritual gene deeply rooted in the blood of the Chinese nation. Since the 18th National Congress of the Communist Party of China, the General Secretary of the Supreme Leader has repeatedly emphasized the importance of labor, profoundly pointing out that "labor is the source of all happiness", "labor is the only way for all success" and "the quality of workers is crucial to the development of a country and a nation".

  Labor creates happiness, and hard work makes great achievements. From standing up, becoming rich to becoming strong, every step of the Chinese nation is saturated with the hard work and silent dedication of hundreds of millions of working people. From Zhao Zhankui, a "flag-bearer of border workers" and Zhen Rongdian, a "flag-bearer of new labor movement" during the new democratic revolution, to Wang Jinxi, an "iron man" and Shi Chuanxiang, who "would rather be dirty than clean" during the socialist revolution and construction, to Kong Xiangrui, a "blue-collar expert" and Deng Jianjun & Hellep, a "knowledge worker" in the new era of reform, opening up and socialist modernization; … It is precisely because of the hard work and selfless dedication of workers that the magnificent building of socialism is built brick by brick. In the new era, a large number of advanced model figures, such as Zhu Shijie, Gao Fenglin, a gold welder, and Huang Dafa, a contemporary foolish man, have made contributions to the motherland and kept pace with the new era, inspiring the broad masses of people to strive to be the strugglers of the new era and writing a new chapter of "Chinese Dream, Labor Beauty". It can be said that all the development achievements made in contemporary China and the happy life enjoyed by the people of China today are made by the working people with their sleeves rolled up.

  This year is the first year to fully implement the spirit of the 20th National Congress of the Communist Party of China, and it is a crucial year to carry out the 14th Five-Year Plan. To do a good job in all aspects of economic and social development and make a good start in building a socialist modern country in an all-round way, we must rely on the people and always serve the people, pay more attention to the role of the broad masses of working people as the main force, and rely on unity and struggle to cope with the situation and start a new one. It is necessary to vigorously carry forward the spirit of model workers, labor spirit and craftsman spirit in the whole society, implement the major principles of respecting labor, knowledge, talents and creativity, and establish the concepts of hard work, honest work and creative work, so that the glory of labor and the greatness of creation will become a sonorous voice of the times. Party committees and governments at all levels should fully stimulate the labor enthusiasm and creativity of the broad masses of working people, effectively protect the legitimate rights and interests of the broad masses of working people, help the broad masses of working people solve problems with heart, and promote the whole society to further form a good atmosphere of advocating labor and respecting workers.

  The grand blueprint for comprehensively promoting the great rejuvenation of the Chinese nation with Chinese modernization has everyone’s share of the achievements and responsibilities. Relying on labor creation to solidly promote Chinese modernization requires the broad masses of working people in China to unswervingly listen to the Party’s words, unswervingly follow the Party, take the goals set by the Party and the state as their own life goals, and consciously integrate life ideals and life struggles into the historical great cause of building a strong country and national rejuvenation. We should work honestly based on our posts, do what we do, love what we do, drill what we do, develop the habit of being good at learning and thinking, enhance the sense of innovation and cultivate innovative thinking, adapt to the needs of the new round of scientific and technological revolution and industrial transformation, study hard and study deeply, constantly improve the level of technical skills, and make extraordinary achievements in ordinary posts.

  "Socialism is done, and the new era is fought." In the face of such an era in which Qian Fan is competing for development, contending for streams, having the opportunity to do business and being able to succeed, as long as the broad masses of working people thoroughly implement the spirit of the 20th Party Congress, unite more closely around the CPC Central Committee with the Supreme Leader as the core, be diligent in creation and be brave in struggle, they will certainly be able to create a new era glory and cast a new historical great cause.

Popular and energetic Big data reflects the new kinetic energy of holiday consumption.

CCTV News:This year’s Mid-Autumn National Day holiday, the national tourism market is hot, and the consumption content and scenes are rich and diverse. According to the data of the Ministry of Culture and Tourism, during the eight-day holiday, the number of domestic tourists reached 826 million, up 71.3% year-on-year, and the domestic tourism revenue reached 753.43 billion yuan, up 129.5% year-on-year. If converted, there are more than 100 million people traveling every day during this holiday.

Deep travel is favored, and tourism consumption has recovered strongly.

Below, take stock of the relevant situation of this holiday trip through big data.

With the help of communication service and computing network, China Mobile Wutong Big Data made a statistical analysis of the national user roaming and communication data, and found that from September 29th to October 6th, the number of tourists and related consumption in various places increased significantly. Among them, the heat of short-distance travel has not decreased, and the long-distance travel has continued to heat up. Short-distance tours within 200 kilometers accounted for 38%; 200— The medium-distance travel of 500 kilometers accounts for 32%; The proportion of long-distance tours over 500 kilometers is 30%. From the perspective of the number of days of tourists traveling, the number of tourists traveling for three days or more accounts for the highest proportion, reaching 60%. Focusing on this group of people, further analysis shows that the proportion of people visiting a city is 65%, indicating that deep travel is becoming more and more popular.

Tourism consumption is concentrated in "three areas and one circle"

This year’s Mid-Autumn National Day holiday, tourism consumption is concentrated in "three areas and one circle", which refers to tourist attractions, resorts, blocks and business districts. These areas have become new tourism and leisure spaces with the most concentrated passenger flow and maximum consumption.

During this holiday, Beijing, Hangzhou, Shanghai, Suzhou and other places have become popular cities for urban roaming. Museums, scenic spots, neighborhoods and other places have actively launched special activities. The "slow time" in the old streets of ancient towns is convenient for tourists to enjoy the "beauty and poetry" at home, find the urban accent in the streets and lanes, and enjoy the beautiful leisure life of the city.

The increasingly perfect urban greenways, theme parks and cultural venues also provide more new spaces for a better life for the diversity and individualization of urban holiday tourism consumption. Urban roaming has driven the heat of urban blocks and business districts to maintain a high level, and the hot spots of tourist consumption have shifted from transportation, accommodation, scenic spot tickets and other fields to shopping, entertainment, catering and other fields.

The consumer market is prosperous and active, and sales are growing steadily and rapidly.

The Ministry of Commerce announced yesterday (October 6) that during the Mid-Autumn National Day holiday this year, the national consumer market was full of popularity and vitality, sales grew steadily and rapidly, sales of green, healthy and intelligent goods increased significantly, consumption of personalized and interactive experience-based services continued to heat up, and the market supply of daily necessities was sufficient and prices were generally stable. According to the business big data monitoring of the Ministry of Commerce, the sales of key retail and catering enterprises nationwide increased by 9% year-on-year seven days before the holiday.

Seven days before the holiday, the passenger flow of national demonstration pedestrian streets increased by 94.7% year-on-year, and the passenger flow of key business districts in 36 large and medium-sized cities increased by 164% year-on-year. The Ministry of Commerce focuses on monitoring the sales of grain, oil, food, beverages, gold and silver jewelry and communication equipment of retail enterprises, which increased by more than 10% year-on-year, while sales of automobiles and cosmetics increased by about 7% year-on-year. The sales of fresh air conditioners, energy-saving water heaters, intelligent sweepers and other products on some e-commerce platforms have more than doubled year-on-year, and some smart and customized home products in home stores are selling well.

The Ministry of Commerce focused on monitoring the sales of catering enterprises, which increased by nearly 20% year-on-year. Chongqing, Hangzhou and Wuhan increased by 30.3%, 19.3% and 16.3% year-on-year, respectively. Family reunions, family dinners, wedding banquets and so on became the hot spots of catering consumption.

Seven days before the holiday, the 200 large-scale wholesale markets of agricultural and sideline products in China had sufficient stocks of grain, oil, meat, eggs, vegetables and fruits, and the average prices of grain and edible oil were basically the same as the week before the holiday.

Unionpay’s online accommodation traffic transactions are among the top growth rates.

According to the data of China UnionPay, online transactions of UnionPay were active seven days before the Mid-Autumn National Day holiday this year. From the perspective of daily average transaction amount, the accommodation industry increased by about 50%, the transportation industry increased by 20%, and the film and television entertainment industry increased by more than 10%. In addition, seven days before the Mid-Autumn National Day holiday, the average daily transaction amount of domestic tourists using UnionPay cards in overseas merchants increased by more than 1.3 times compared with the same period of last year. Scenes such as catering, duty-free shops and department stores were among the top gainers. 

As of 0: 00 today, the National Day movie ticket room exceeded 2.73 billion yuan.

In terms of movie box office, preliminary statistics show that as of 0: 00 today (October 7), the total box office of National Day movies in 2023 exceeded 2.73 billion yuan, with a total audience of 64.79 million and a total number of performances exceeding 3.52 million. During the Mid-Autumn National Day holiday, a number of domestic new films were released in a concentrated way, bringing diversified viewing options to the audience.

The new fashion of tourism consumption reflects the new vitality of economy.

During the Mid-Autumn National Day holiday, the national consumer market is full of popularity and vitality, and the enthusiasm for traveling is concentrated, enjoying convenience, emphasizing experience and loving sports. How do these new consumption trends reflect the new vitality of the economy? Look at the expert’s analysis.

Dai Bin, Dean of china tourism academy:Throughout the holiday, the travel willingness and tourism consumption of urban and rural residents have been maintained at a high level, creating the highest tourism fever in history since the monitoring record, with an average of more than 100 million people traveling every day. On the whole, we had a safe, stable, peaceful and joyful Mid-Autumn National Day holiday.

The integration of culture and tourism, art and tourism has become more and more abundant. In addition, we have another feature this year, "sports+tourism, art+tourism, music+tourism" is increasing. When tourists travel, the content scenes of consumption are more and more abundant in tourist destinations. Diversification and personalization constitute a very prominent feature of tourism consumption in this holiday, regardless of all aspects and elements of eating, living, traveling, shopping and entertainment.

This holiday, the increasingly perfect urban greenways, theme parks and cultural venues provide more new spaces for a better life for the diversity and personalization of urban holiday tourism consumption.

Dai Bin, Dean of china tourism academy:In the process of transformation from scenery to scene, don’t think that the city is just reinforced concrete, and the city concentrates the most creative and advanced elements of culture and commerce. We will suddenly find that after staying in a city for so long, I didn’t know the city. I hurried to work every day, hurried off work, and went away after a holiday. We will find that things around us didn’t understand. This is a deep logic, that is, a good life starts from the side.

Jietu also dare not underestimate, wet dual clutch (DCT)+ front drive.

There are many people who blindly look at the vehicle dynamic parameters when buying a car. In fact, the greater the value, the better the experience. The competition in the automobile market is still very fierce. What Xiaobian brings today is. Let’s take a good look at it.

First of all, from the appearance, the front of Jetway X90 gives people a very clean feeling, and it is equipped with a hexagonal grille, which makes people unforgettable. Combined with headlights, it is in line with consumers’ aesthetics. The car is equipped with LED daytime running lights, automatic opening and closing, delayed closing and so on. Coming to the side of the car body, the size of the car body is 4858 mm * 1925 mm * 1780 mm. The car adopts dynamic lines, and the side wall presents a stable and atmospheric design style. With large-size thick-walled tires, the shape is quite cool. In the rear design, Jetway X90′ s rear line is solid, the taillight style is exquisite, and it is very simple with bilateral single exhaust pipes.

Sitting in the car, the interior design has taken the fashion sports route, giving people a very hard-core feeling. The steering wheel of the car is very simple in shape, equipped with the functions of manual steering wheel up and down+front and rear adjustment, and the grip performance is good. Let’s take a look at the central control. The car is equipped with a deep touch-control LCD central control screen, which makes the interior style impressive and looks fashionable and simple. The interior feels good. Let’s take a look at the dashboard and seats. The dashboard of the car presents a fashionable and simple design style, and the trendy design elements make people remember it at a glance. The car uses a leather-like seat, and the seat is wrapped in place, which is very comfortable to ride.

The Jetway X90 is matched with a wet dual clutch (DCT) gearbox, with a maximum power of 145KW and a maximum torque of 290N.m, with good power performance.

Jietu X90′ s rear row space is quite satisfactory, and the legroom is fairly rich, so there is no problem in meeting daily household needs. In addition, the car is equipped with anti-lock braking system (ABS), LED daytime running lights, brake assist (EBA/BAS, etc.), braking force distribution (EBD), traction control (ASR/TCS, etc.), main driver airbag and co-pilot airbag.

Such a car with the right price is enough to meet the daily practical needs, and it doesn’t take much thought to maintain it at ordinary times, and the cost performance is good. If you are concerned, you might as well experience it.

Great Wall Euler released the right to buy a car in October: the good cat starts at 95,800 yuan, and the lightning cat has a maximum discount of 60,000 yuan.

On October 5 th, Great Wall Motor’s Euler brand released its car purchase rights in October on the 4 th, including 2024 Euler Good Cat/GT Mulan Edition, Euler Ballet Cat, Euler Lightning Cat and other models.

The specific benefits of IT House are summarized as follows:

According to the previous report of IT House, the sales volume of 108,398 vehicles of Great Wall Motor in September dropped by 10.88% year-on-year, including 44,105 overseas vehicles and 30,129 new energy vehicles, with a total of 211,492 vehicles from January to September. Among them, the sales volume of Euler brand in the month was 5486, compared with 10021 in the same period last year.It fell by 45.25% year-on-year.

Beijing Benz EQE is officially listed, with a price of 528,000-585,000 yuan.

On the evening of August 24th, Beijing Benz EQE was officially launched, and three new models were launched, with a price of 528,000-585,000 yuan. The new car is positioned in a pure electric medium and large car, and the maximum cruising range can reach 752km under CLTC working conditions.

The overall appearance of the new car is fashionable and handsome, and it is equipped with a fully enclosed air intake grille that perfectly connects with the unique headlights on both sides, becoming an overall design and very individual. The profile of the car side is full and exquisite. The tail is equipped with a "duckling tail", which is slightly upturned and more dynamic. The through LED light group makes the new car look more spacious and highly recognizable.

In terms of size, the length, width and height of the new car are 4969/1906/1514 mm, and the wheelbase is as long as 3120 mm. The unique shape makes it look different from such a large-sized car. In addition, it is also an exaggerated proportion to make a wheelbase of 3.12m within the length of 5 meters!

In terms of interior, the shape is similar to the overall style of the new generation S-class. The instrument panel is suspended, and the large screen is embedded in the center console. There are many styles of materials in the car. The front platform is decorated with wood grain, the armrest area is decorated with piano paint, and of course there are a lot of soft materials! Still using the bosom block design.

In terms of intelligence, the new car is equipped with a 12.3-inch instrument+a 12.8-inch central control panel, or an MBUX intelligent human-computer interaction system. The contents of the car are presented through a zero-level interface. The Xavier chip in NVIDIA is first-class in both UI design and screen quality, but the logic definition has its own gameplay, which requires a learning process.

In terms of configuration level, digital headlights are very powerful (2.6 million pixels), frameless doors are also very sensual, with AR real-life navigation, wireless CarPlay, active ambient light, and the rear wheel turns 10. There are 15 speakers in the Voice of Berlin ~ Some localized configurations have been added for China, such as the design of rear central armrest, front wireless charging function and comfortable rear headrest.

In terms of power and endurance, the maximum power of single motor and dual motor is 215kW and 300kW respectively, and the maximum torque is 556N·m and 858N·m respectively. The 100-kilometer acceleration time of the dual-motor model is 4.7 seconds. In terms of battery life, the cruising range of EQE350 Pioneer Edition is 752km, and the deluxe edition and the first special edition are both 717km. The cruising range of the dual-motor EQE500 4MATIC version is 658km. 128kW DC fast charge, the power is from 10-80% in 48 minutes.

The previous EQXX has pointed out the development direction of Mercedes-Benz’s electrification, that is, lightweight and ultra-low wind resistance. Therefore, in the future, EQ series cars should maintain this ultimate orientation in the pursuit of "low wind resistance modeling". The maximum battery life of 752 kilometers under CLTC working conditions is indeed exaggerated. Before the breakthrough in charging speed has been formed, higher battery life means stronger product strength!

Zhao Youting suffers from "award phobia" refreshing endorsement to support Ruan Jingtian


Zhao Youting endorses


Zhao Youting endorses

 

  Recently, Zhao Youting became the annual spokesperson of a brand’s men’s series with the image of "Extremely Clean New Men". Although the advertisement of playing basketball in the sun showed a confident side, he actually suffered from a serious "fear of winning awards". When he learned that he had squeezed out Zaizai and was shortlisted for the "Magnolia Award" for the Shanghai TV Festival with "Ruffian Hero", his first thought was: "What should I do?" 

  Zhao Youting and his rumored girlfriend Zhang Junjun have respectively become the spokesmen for a certain brand’s men’s and women’s series. He attended a press conference a few days ago, and he could guess what the reporters would ask in advance. Like Ruan Jingtian, who has been in turmoil recently, Zhao Youting said that when he was criticized after winning the Golden Bell Best Actor, Xiao Tian comforted him that "he can get by, and everything will pass". Now he believes that Xiaotian will get by too. 

  However, "Mengka" will face a possible competition for the best actor this year. Zhao Youting said that although he hopes his acting skills can be recognized, he does not like to compete with others: "I don’t want to win the award now, and I will win it after 30 years old." He admitted that he was extremely surprised to know that he was the only Taiwanese actor shortlisted for the "Magnolia Award" because the mainland did not broadcast "Ruffian Hero" at all, and he was afraid of winning the award again. "I used to be happy, but now I only worry." 

  Leaving aside the landmine of winning the award, Zhao Youting has become more and more able to withstand jokes. Although he shoots Neutrogena advertisements with dew points, he clenches his arms and tries not to let his armpits float out. He laughs and says that because Xiaotian’s armpits are more "beautiful", they are not too sparse or a big tuft, but they are soft and smooth, which makes the audience laugh. If it were Zhao Youting in the past, he might have frowned and frowned: "Why don’t you talk about acting, but you should care about my armpits?" But after a year of baptism, he has been able to do it with ease. He does look like a "white beheaded chicken" in the photo of the advertisement, and his face is swollen like he has been punched.
 

Peng Yuyan: Strongly through the desolation

Original Madame Figaro Madame Figaro

Forging and polishing the body as the container of the character, extreme self-discipline, concentration, and almost symbolic masculine aesthetic template, these characteristics related to beauty and will character constitute Peng Yuyan, or rather, the established impression of Peng Yuyan facing the outside world. After more than 20 years in the industry, the accumulated works have continuously consolidated this side. Peng Yuyan is no longer a name, but a label bound to many entries.

When he leads his dog on the red carpet and beach in Cannes, people are in a trance for a moment: Peng Yuyan is actually 42 years old? – Yes, he has reached the age of a middle-aged actor, and time has left natural marks on his face. In the upcoming movie "Dog Formation", Peng Yuyan plays a northwestern man released on parole, dark, hunched, silent, and almost without lines. On the cold and desolate Gobi, forsaken by human society, he and an equally lost black dog depend on each other and redeem each other.

After the film was completed, he adopted the partner who helped him complete most of the filming and named him Xiao Xin. On May 24, "Dog Array" won the Best Film Award in the "One Kind of Attention" section of the 77th Cannes Film Festival by a unanimous vote. Xiao Xin also won the "Golden Palm for Dogs" jury award specially designed to honor animals at the Cannes Film Festival. Peng Yuyan accepted the award on his behalf. He smiled and teased that he came to Cannes with the "Roll! Ashin" crew 13 years ago, but did not win the award. Xiao Xin won the award the first time he came.

At the seaside of Cannes, passers-by asked Xiao Xin’s name was "Xin" of "Hard"? He gently corrected: It was Xin of Cinderella.

Like Erlang in "Dog Formation", he is also back on the road. With Xiao Xin, there is also a stable heart.

Before "Dog Array," Peng Yuyan had not been filming for two years. The pause button was initially pressed by the environment, and he himself wanted to seriously consider the next development direction, so the pace naturally slowed down. Over the past decade or so, his amazing will for movies and performances has become a self-discipline sample: substantial muscle gain, fat loss, various professional-level skills, high cooperation without fear of hardship, and willingness to "suffer". The director who has worked with him commented, "Peng Yuyan can use his soul to command the body. He doesn’t care how much damage, laziness and coquetry his body has."

When suffering becomes the norm, the outside world is naturally full of curiosity and inquiry, and the bitter swallower himself can only give his own answers again and again in interviews and inquiries. In this interview, the 42-year-old Peng Yuyan was much more peaceful, just smiled lightly, "I need a breakthrough point and landing point for the performance, otherwise how can I act? The process of preparation and learning can help me enter faster. Is there a real happy creation in the world? I want to say I have it, that would sound cool, but it turns out that I don’t, I really don’t have it."

In this industry, "hand familiarity" is almost non-existent, and any actor with creative requirements will tighten in front of the camera, hoping to give an expression that meets the standard or breaks through his own. Peng Yuyan has expressed his reverence for acting more than once, and to this day he still worries that he will not be able to act well and that the homework for the role is not enough. "There are still a lot of helplessness and doubts in the acting, and there are too many uncertainties in the process. But I can’t help it. I try my best to do it, and I can only believe in myself at that time."

When the cast of "Dogs" was announced, some netizens expressed skepticism that Peng Yuyan, who is regarded by the public as tall and handsome, is difficult to connect with the social fringes released on parole in small towns in the west. But after the film was screened in Cannes, it received a warm response. Zavier Dolan, who is the chairperson of the jury of the "One Focus" section, said, "This is a master director’s work."

The story takes place in 2008 in a small town on the northwestern border. Peng Yuyan plays Erlang, who is released from prison on parole. He has a shaved head, dark complexion, and a little hunched back. From time to time, he purses his lips and shrinks, his eyes are indifferent and dull, and he is full of vigilance and defense. The whole film may only have dozens of words, and the silence that borders on aphasia also represents Erlang’s departure and break from society. Because of his special status, he is banned from leaving the town and has no hope of a new life. Forced to make a living, he can only join the local dog fighting team that rounders up stray dogs.

In the pursuit of a black dog suspected of carrying rabies virus, Jiro and the black dog "don’t bite and don’t know each other". It is also because of the mutual company and redemption of the black dog that Jiro has gained the courage to go back on the road and break through the "array" that once limited him. The film’s tone is cold, and there are a lot of large-scale vistas of the desolate landscape of the Gobi, where one person and one dog are particularly insignificant. But even such a person who struggles to survive in harsh weather and embarrassing situations still has real desires and dreams. He wants to have a new life.

Unlike most of Peng Yuyan’s screen images, the character of Erlang can be said to have nothing to do with good-looking, and the whole person is withdrawn and gloomy. In order to be close to the identity and local environment, he has to be tanned and rough, and with aphasia and silence, the performance can hardly be expressed by lines. Peng Yuyan initially received the script and thought Erlang was dumb. "Later, it was found that he did not know how to speak, but did not want to speak. He took the initiative to cut off the language and only communicate with people he trusted. This made me feel quite challenged."

Before 2020, Peng Yuyan had been in a state of intense output, shooting seven consecutive plays in one year. His screen image ranged from gymnast to police officer, college student to air-conditioning repairman, and the role map was very broad. But the role of Erlang, Peng Yuyan admitted that it was unprecedented, "I really want to experience this process from the perspective of an observer. And the timing is quite coincidental. I got this script at the age of 40, and it has a strong touch and resonance. If I had seen it ten years earlier, I might not have had these empathy."

There was another reason why Peng Yuyan was moved by the love of the director Guan Hu. "I think the director is a person who loves animals very much." He counted the director’s previous works, "Bullfight", "Killing Life", "Old Pao’er" and "Eight Hundred", all of which had various animal shoots.

The filming was concentrated in Guazhou and Yumen, Gansu Province, where the climate was dry and the ultraviolet rays were strong. Peng Yuyan went to experience life in advance, and learned about the customs, living habits, and intonation and accent. These preparations were no different from every time he entered the group in the past. Step by step, he started to change from the environment and moved closer to the role. But there were also very different content from the past. For example, he didn’t have to over-carve his muscles, and his training programs were replaced by motorcycle and animal rehearsals. The crew hired a professional team to train animal actors, and he also had a lot of training to do.

Animals are extremely difficult to shoot, and there are many uncontrollable factors. There are hundreds of dogs on the crew of "Dog Formation", as well as tigers and other large animals in the zoo plot. These all require Peng Yuyan to rehearse in advance to reduce mistakes on the scene. "Animals are not actually performing, they are just showing natural and real reactions, obeying human instructions, and each reaction may be different," he smiled, feeling that he had become the one being taken away, "I will be influenced, I am not acting, everyone is the real performance."

The director Guan Hu also mentioned in the Cannes interview, "It’s more important to pay attention to the wildness of Peng Yuyan. In many movies, it is difficult for him to show the strong wildness and the loneliness in his body. In fact, he doesn’t need to act. As long as he is given a state, he will naturally show it."

In the film, Jiro tried several times to ride a motorcycle out of the town, but failed. One of the falls, Peng Yuyan has a shot of wiping the blood on his forehead with his hand, with a bit of the mythical mystery of Erlang’s eyes opening, indicating that he is about to break through his inner demons.

However, Peng Yuyan did not specify where Jiro’s awakening was. He felt that the artistic judgment should still be handed over to the audience. After the performance was edited and arranged differently, the final feeling belonged to the audience.

In reality, when I really came into contact with Peng Yuyan, I couldn’t feel the "wildness" that Director Guan Hu said at all. His speech was low-pitched, he loved to laugh, and occasionally he would make a few humorous jokes. In addition, this time he brought Xiao Xin, and he had to appease his emotions from time to time. The whole persona is very soft. "I also hope to say that I can create happily, and I can act simply and easily, but I still want to tell everyone that the filming is not as good as I thought. Sorry, it’s a little ruining my beautiful imagination," he smiled wryly, "Sometimes it rains half the time, or when I have a meal, I have to wait until I come back and then shoot. The mood has been broken, and the state of the human and the dog is not compatible, so I can shoot again, and I can’t help it

But there was a small detail that flashed by, but it could give a glimpse of how he and Jiro fit together –

"Peng Yuyan, who has been repeatedly discussed and written by the outside world, what are the differences between the Peng Yuyan you personally know?"

After listening to it, he almost didn’t think much about it, and immediately replied: "I don’t even know what kind of person I am, and I’m still looking for it. The outside world’s opinions definitely don’t represent all of me. The online world we are in contact with now is used to showing the delicate and beautiful side, but good or bad, I am myself. It’s normal for others not to know or misunderstand, and I don’t care that much about it."

Jiro is speechless and withdrawn. He doesn’t care about the outside world’s opinions, and he doesn’t care about his own injuries. He just wants to ride a motorcycle and leave the town. As a result, he rolls around in the wind and sand, and bleeds in embarrassment. But if you can’t do it once, you have to come again. He is a marginal person in society, but he also has a little enthusiasm in his heart. When he met this role at the age of 40, Peng Yuyan felt that the timing was right. "He gave me some new ideas about the emotional communication between humans and animals, including my own cognition and pursuit of performance. Animals are very simple. They live in the moment and will not hide their feelings. They can receive the kindness and sincerity you release. Now it is all about emotional internal friction. I think it may be that the desire and self-awareness are too strong? You see, I only live with dogs in the play, what’s the point of internal friction, right? "

During his time in Cannes, photos of Peng Yuyan walking his dog on the red carpet and being met by passers-by while walking his dog on the beach appeared frequently on domestic social platforms, and the comment section praised his relaxed state. This is in sharp contrast to the extreme self-discipline that once became his label, and it is also like a strange intertext of fate – Peng Yuyan has indeed entered a new stage of life.

After the pace of work slowed down, Peng Yuyan spent more time with his family and enriched himself. He was very filial to his mother, and he took her to travel around the world when he had time, including this time at Cannes, to share the joy of winning awards directly with his mother. Studio footage recorded him and his mother hugging and cheering, like lively children. During the previous period of recuperation, he also accompanied his mother to do various experiments. "I will accompany my mother to practice the piano and take piano lessons with her. I follow my teacher to learn pottery by myself, sometimes practice calligraphy, read the" Tao Te Ching ", and meditate. The main thing is to experience a lot of different things, and my family likes to do them together."

Before coming to France, Peng Yuyan was deeply impressed by the scenery and architecture of Nice and Lyon, as well as the flower fields of Provence. At that time, he also took his mother to the nearby "clay city", Roussillon, where the soil is rich in red ochre sand mines, famous for its magnificent red cliffs, orange-red house facades and ochre quarries. The town was originally named Viscus Russulus, which means "red mountain" in Latin. The aerial view of the picture is full of red, and it looks full of vitality. – Peng Yuyan introduced with great interest, trying to pronounce the word starting with R, with a serious and funny expression. Everyone laughed.

"I remember that there are shows everywhere near Red Earth City, so I took my mother to play. The houses over there are also red and orange, which is very beautiful. After the ochre is mined, there will be large mines that turn into caves. We watched the projection animation in it, and it felt great."

Of course, the trip was also deeply touched. Peng Yuyan also went to see the room where Van Gogh lived before his death, just like the painting of "Van Gogh’s Bedroom in Arles". The room was low and narrow, and it did not look so comfortable. He also thought about the artist’s creation and life there, some things that were not pleasant and light. As an actor, the sensitivity of the senses cannot be turned off, and it will be hit at any time.

He had to admit that there were too many moments when he was "hit", and there were many moments of confusion and pain in his life, and the tempering from the body was only part of it. "This question is too difficult," he began to smile bitterly again, "There are so many things happening in the world every day, and there are all kinds of natural and man-made disasters. If emotions can be put into words, wouldn’t it be too simple? After all, people are so complicated."

Just now, he was still talking about how he only lived with dogs when filming "Dog Formation", which was easier than people. Soon, the interview questions from human society stumped Peng Yuyan. "You will ask me how my birthday was, how my life changed, who remembers?" He laughed in distress, showing a child-like expression, but complaining was a complaint, but he still racked his brain to recall, and took the answer out of his head, "Oh, I remember! I’m taking a break for my birthday this year. In the past, every birthday was filming, and it was rare to take a break this year."

In his early twenties, Peng Yuyan made a name for himself by his hard work. After the age of thirty, these hardships were left on his body as medals, along with the wounds and scars left by training and shooting. In the interview during the promotion stage of the movie "Emergency Rescue", he said that the wounds and scars he fell in the past still itch at night. But people rely on their will to survive and use their energy in what they think is right. Now in his forties, he wants to save energy for things he likes in the future, and when he encounters the moment to fight again, he will fight again.

"Experience, I came to this world to experience," he chose to accept all the feelings that appeared, "There is a voice deep in our hearts that we may not be able to hear, but intuition exists, guiding us to do something. I like to climb mountains and go to sea, ski and ride, go to different places around the world to see different cultures, these energy from the outside world are injected into the body, very happy."

If you are not happy occasionally, it doesn’t matter. Peng Yuyan recently received "One Hundred Years of Solitude" from a friend. In the long story, there are so many ups and downs, but the book is over when closed. Returning to his own life, he believes that the key is "forgiveness", "People will be internal friction and fragile, but that is still myself. If it is not good or perfect, I will forgive myself, and these shortcomings will not affect me to become a complete and real person at all."

Produced by PRESENTED KAN Hongjie

Producer & Styling SUPERVISOR & STYLING Chen Liming

PHOTOGRAPHY Alex Huanfa Cheng

SHOOTING COORDINATION French fries

MAKE UP Jane Weiwen

HAIR Yun

Produced by PRODUCER Mai Mai

Interview & Writing INTERVIEW & WRITER Gu Xiang

Video Director VIDEO DIRECTOR Shen Hui

FASHION ASSISTANT Guo Lei, Zi Qi

COVER DESIGN Zhao Youjia

Original title: "HOMMES Cover Story | Peng Yuyan: Strongly Through the Desolation"

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